Nicotine makes your heart rate go up by 2 to 3 beats a minute. It also raises blood pressure in the short term because it narrows (constricts) blood vessels. Nicotine reduces blood flow to the heart.

This neurotransmitter makes a "natural high" within 7 to 10 seconds of inhaling. Nicotine stimulates the central nervous system. It also decreases the sense of pain.

Nicotine changes nerve signals that control physical actions, behavioral control, and memory. That's why a certain remembered scene or a smell can trigger a craving for cigarettes.

Stress is also one of the main reasons given for relapsing when trying to quit. Everyone has stress in their life, but smokers use nicotine to help them cope with stress. When trying to quit, a smoker needs to find other ways to cope with stress.

E-cigarettes haven’t been approved by the FDA as an aid to quit smoking. It's unclear if they can actually help with quitting. And they may be harmful. Serious lung conditions have been linked to vaping. This includes e-cigarette or vaping product use associated lung injury (EVALI). Some people have died from the lung conditions. Also, second-hand smoke from hookahs can be a health risk for nonsmokers. Talk with your healthcare provider about other ways to quit that are safe and that work well.

Your healthcare provider may be able to prescribe a medicine that can help you quit using nicotine. There are also over-the-counter medicines that work well to help people quit smoking.

Tobacco dip and snuff actually have more nicotine than cigarettes. Holding dip in your mouth for 30 minutes can give you as much nicotine as smoking 4 cigarettes. Two cans of snuff have as much nicotine as 10.5 packs of cigarettes.

Studies have shown that working with others to help you quit works better than trying to quit on your own. People who talk with a healthcare provider in person or on the phone, or go to support groups have better success rates. You can also find good online resources and support groups. The American Lung Association and the CDC are two good places to start looking for resources and support.