• Wash your hands well with soap and water.

• Prepare the medicine (if needed).

• Sit or stand in a comfortable position in a warm, well-lit room. If you need to, sit or stand in front of a mirror.

• Find an injection site on one side of your penis, in a place with no visible veins. (Don’t inject into the top, bottom, or head of the penis.)

• Clean the injection site with an alcohol swab. Grasp the head of your penis firmly with your thumb and forefinger (don’t just pinch the skin). Stretch the penis so the skin on the shaft is taut.

• Rest your penis against your inner thigh and pull it gently toward your knee. Don’t twist or rotate it. This way you’ll be sure to inject the medicine into the spot you chose and cleaned before.

• Hold the syringe between your thumb and fingers, like you’re holding a pen. Rest your forearm on your thigh for support.

• Insert the needle at a 90° angle (perpendicular) to the shaft. Do this quickly to reduce discomfort. (The needle should go in easily. If it doesn’t, stop right away.)

• Move your thumb to the plunger. Press down to inject the medicine, counting to 5.

• Remove the needle and dispose of it safely.

• Apply pressure to the injection site for a few minutes. This prevents swelling and bruising. It also helps spread the medicine. 

• Stand up. This may help your erection develop. Foreplay often helps, too.

• Your penis should become firm within  10 to 20 minutes. The erection will last long enough for sex, and maybe longer.

Go to the closest emergency department if you have an erection that lasts longer than  3 to 4 hours. Erections that last longer than 4 hours can damage the penis and lead to permanent ED.

Call your healthcare provider if you have:

• Bleeding or bruising

• Severe pain

• Scarring or curvature of the penis