March 22, 2017



Natural Standard Monograph, Copyright © 2013 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Related Terms

  • Akebia, anti-inflammatory, atopic eczema, dermatology, dictamnus, eczema, licorice, lophatherum, potentilla, red peony, rehmannia, schizonepeta, siler, tribulus.

  • For more information on individual herbs, please see Natural Standard's Herbs & Supplements Database.


  • Zemaphyte® is a Chinese herbal remedy produced in the United Kingdom. The remedy contains licorice and nine other herbs. Zemaphyte® is most commonly used to treat steroid resistance eczema, childhood and adult eczema as well as atopic eczema.

  • The powder formulation of Zemaphyte® is normally dosed according to packets. One or two packets is mixed in hot water and drank once a day.

Common Name/Pin Yin

Botanical Name

TCM Category Description

Siler (fangfeng)

Ledebouriella seseloides

dispel wind, relieve surface

Potentilla (baitougweng)

Potentilla chinensis

clear heat, dry damp

Akebia (mutong)

Clematis armandii

dry damp, promote diuresis

Rehmannia (dihuang)

Rehmannia glutinosa

clear heat, cool blood

Red peony (chishao)

Paeonia lactiflora

vitalize blood, clear heat

Lophatherum (danzhuye)

Lophatherum gracile

clear heat, purge fire

Dictamnus (baixianpi)

Dictamnus dasycarpus

clear heat, clean toxin

Tribulus (baijili)

Tribulus terrestris

calm wind

Licorice (gancao)

Glycyrrhiza glabra

remove toxin

Schizonepeta (jingjie)

Schizonepeta tennuifolia

dispel wind, relieve surface


  • Zemaphyte® is proposed to exhibit it's main effects by producing an anti-inflammatory response as well as act as an immunomodulator or immunosuppressive agent.

  • Zemaphyte® has been proven in numerous clinical trials to reduce skin surface damage, erythema (redness of the skin) and itching as well as improve sleep quality.

  • A randomized, placebo controlled trial comparing Zemaphyte® to other Chinese herbal remedies commonly used for eczema found that the patients who used Zemaphyte® had less surface damage, less redness and better sleep than patients who used other Chinese herbal remedies.

Side Effects/Drug Interactions

  • Zemaphyte® has been associated with elevated liver function tests, diarrhea, uticaria (hives) as well as other rare but serious side effects.

  • Zemaphyte® has been shown to interact with methotrexate.

  • A qualified healthcare provider should be consulted before making decisions about therapies and/or health conditions.

Author Information

  • This information has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).


Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

  1. Vender RB. 20 October 2006. www.skintherapyletter.ca

  2. Zhang W, Leonard T, Bath-Hetal F, et al. Chinese herbal medicine for atopic eczema. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD002291. View Abstract

Copyright © 2013 Natural Standard (www.naturalstandard.com)

The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.


March 22, 2017