What is this medicine?
ZIPRASIDONE (zi PRAY si done) is used to treat schizophrenia and bipolar disorder, also known as manic-depression.
How should I use this medicine?
This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
change in emotion or behavior such as feeling depressed, angry, or anxious
excessive thirst and/or hunger
fast or irregular heartbeat or palpitations
fever or chills, sore throat
frequently needing to urinate
inability to control muscle movements in the face, hands, arms, or legs
loss of balance or difficulty walking
lump or swelling on the neck
redness, blistering, peeling or loosening of the skin, including inside the mouth
stiff muscles or jaw
uncontrollable movements or spasms of the face, tongue or mouth
weakness or loss of strength
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain antibiotics like clarithromycin, erythromycin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
certain medicines for depression
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like amiodarone, dofetilide, dronedarone, flecainide, procainamide, quinidine, sotalol
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
phenothiazines like chlorpromazine, mesoridazine, thioridazine
This medicine may also interact with the following medications:
certain medicines for blood pressure
certain medicines for Parkinson's disease
stimulant medicines for attention disorders, weight loss, or to stay awake like amphetamine, dextroamphetamine
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes or high blood sugar
heart disease, including heart failure
low potassium level in the blood
Parkinson's disease or other movement disorders
previous heart attack or stroke
suicidal thoughts, plans, or attempt by you or a family member
an unusual or allergic reaction to ziprasidone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
July 17, 2018