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What is this medicine?
VORICONAZOLE (vohr ih KON uh zohl) is an antifungal. It stops the growth of some fungus and yeast. This medicine is used to treat many kinds of fungal infections.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least one hour before or one hour after a meal. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
changes in vision
rash, fever, and swollen lymph nodes
redness, blistering, peeling, or loosening of the skin, including inside the mouth
signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast, irregular heartbeat; palpitations; feeling faint or lightheaded; falls; breathing problems
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Do not take this medicine with any of the following medications:
barbiturates like phenobarbital
certain antibiotics like rifabutin, rifampin
certain medicines for cholesterol like atorvastatin, lovastatin, simvastatin, lomitapide
certain medicines for irregular heart beat like dronedarone, quinidine
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
St. John's wort
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
birth control pills
certain medicines for blood pressure like amlodipine, nifedipine
certain medicines for cancer like vinblastine, vincristine
certain medicines for depression, anxiety, or psychotic disturbances like alprazolam, midazolam, triazolam
certain medicines for diabetes like glipizide, glyburide, tolbutamide
certain medicines for pain like alfentanil, fentanyl, methadone, oxycodone
certain medicines for stomach problems like omeprazole
certain medicines that treat or prevent blood clots like warfarin
medicines that lower your chance of fighting infection like cyclosporine, everolimus, tacrolimus
NSAIDS, medicines for pain and inflammation, like diclofenac, ibuprofen
other medicines for fungal infections
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
history of irregular heartbeat
an unusual or allergic reaction to voriconazole, other antifungal medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
You may need blood work done while you are taking this medicine.
Tell your health care professional right away if you have any change in your eyesight.
This medicine can make your more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps or tanning beds/booths.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Women should inform their health care professional if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects and harm to an unborn child. Talk to your health care professional for more information.
November 27, 2020