Voretigene neparvovec injection

What is this medicine?

VORETIGENE NEPARVOVEC (vor ET i jeen ne PAR voe vek) is a gene therapy used to treat a certain form of inherited vision loss.

How should I use this medicine?

This medicine is for injection into the eye. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• bleeding from the eye

• changes in vision

• eye pain

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• eye disease, vision problems

• an unusual or allergic reaction to voretigene neparvovec, other medicines, foods, dyes, or preservative

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

Tell your doctor or health care professional right away if you have any change in your eyesight.