Trovafloxacin, Alatrofloxacin
Trovafloxacin, Alatrofloxacin injection
What is alatrofloxacin injection?
ALATROFLOXACIN (Trovan™ IV) is a fluoroquinolone antibiotic. Alatrofloxacin kills certain bacteria or stops their growth. It treats severe infections of the blood, pelvic area, skin, and lungs. Generic alatrofloxacin injection are not yet available.
What should my health care professional know before I take alatrofloxacin?
They need to know if you have any of these conditions:
arteriosclerosis
liver disease
prolonged exposure to sunlight (working outdoors)
seizures (convulsions)
stomach problems (especially colitis)
stroke
an unusual or allergic reaction to fluoroquinolone antibiotics, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take this medicine?
Alatrofloxacin is for slow infusion into a vein, usually over 60 minutes. It is usually given by a health care professional in a hospital or clinic. If you are told to give yourself infusions of alatrofloxacin, make sure you understand the procedure and follow the directions carefully. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with alatrofloxacin?
aluminum salts
antacids
calcium salts
doxercalciferol
iron (ferrous sulfate) preparations
magnesium salts
manganese
medicines for diabetes
multivitamins containing iron, calcium, zinc, or manganese
NSAIDs such as Advil®, Aleve® ibuprofen, Motrin®, naproxen
sodium citrate
sucralfate
zinc salts
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking alatrofloxacin?
Tell your prescriber or health care professional if your symptoms do not improve in 2 to 3 days.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how alatrofloxacin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.
Drink several glasses of water a day. Cut down on drinks that contain caffeine.
Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.
What side effects may I notice from taking alatrofloxacin?
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
confusion
convulsions
difficulty breathing
hallucinations
increased sensitivity to the sun
joint, muscle or tendon pain
nightmares
redness, blistering, peeling or loosening of the skin, including inside the mouth
severe or watery diarrhea
skin rash, itching
swelling of the face or neck
tremor or restlessness
vision changes
vomiting
yellowing of the skin
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
constipation or diarrhea
difficulty sleeping
dizziness or drowsiness
headache
nausea or stomach upset
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Store at a temperature between 15 degrees C to 30 degrees C (59 degrees F to 86 degrees F). Protect from light. Do not freeze. Throw away any unused medicine after the expiration date.
Trovafloxacin, Alatrofloxacin tablets
What are trovafloxacin tablets?
TROVAFLOXACIN (Trovan™) is a fluoroquinolone antibiotic. Trovafloxacin kills certain bacteria or stops their growth. It treats severe infections of the blood, pelvic area, skin, and lungs. Generic trovafloxacin tablets are not yet available.
What should my health care professional know before I take trovafloxacin?
They need to know if you have any of these conditions:
arteriosclerosis
liver disease
prolonged exposure to sunlight (working outdoors)
seizures (convulsions)
stomach problems (especially colitis)
stroke
an unusual or allergic reaction to fluoroquinolone antibiotics, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take this medicine?
Take trovafloxacin tablets by mouth. Follow the directions on the prescription label. Swallow tablets whole with a full glass of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with trovafloxacin?
aluminum salts
antacids
calcium salts
doxercalciferol
iron (ferrous sulfate) preparations
magnesium salts
manganese
medicines for diabetes
multivitamins containing iron, calcium, zinc, or manganese
NSAIDs such as Advil®, Aleve® ibuprofen, Motrin®, naproxen
sodium citrate
sucralfate
zinc salts
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking trovafloxacin?
Tell your prescriber or health care professional if your symptoms do not improve in 2 to 3 days.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how trovafloxacin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.
Drink several glasses of water a day. Cut down on drinks that contain caffeine.
Antacids can stop trovafloxacin from working. If you get an upset stomach and want to take an antacid, make sure there is an interval of at least 2 hours since you last took trovafloxacin, or 6 hours before your next dose.
Iron and zinc preparations can also stop trovafloxacin from working properly.
Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.
Discontinue trovafloxacin and contact your physician if you notice pain or swelling of a tendon or around a joint. If you notice any of these symptoms while taking trovafloxacin, do not exercise until you have been checked by a prescriber or health care professional.
What side effects may I notice from taking trovafloxacin?
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
confusion
convulsions
difficulty breathing
hallucinations
increased sensitivity to the sun
joint, muscle or tendon pain
nightmares
redness, blistering, peeling or loosening of the skin, including inside the mouth
severe or watery diarrhea
skin rash, itching
swelling of the face or neck
tremor or restlessness
vision changes
vomiting
yellowing of the skin
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
constipation or diarrhea
difficulty sleeping
dizziness or drowsiness
headache
nausea or stomach upset
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Store at a temperature between 15 degrees C to 30 degrees C (59 degrees F to 86 degrees F) in tight containers. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert