Trifluoperazine
Trifluoperazine Hydrochloride Oral tablet
What is this medicine?
TRIFLUOPERAZINE (trye floo oh PER a zeen) is used to treat schizophrenia. This medicine may also be used for the short-term treatment of anxiety.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood disorders or disease
dementia
head injury or coma
liver disease
Parkinson's disease
uncontrollable movement disorder
an unusual or allergic reaction to trifluoperazine, other medicines foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
amoxapine
certain antibiotics like gatifloxacin, grepafloxacin, sparfloxacin
cisapride
clozapine
droperidol
ephedrine
kaolin; pectin
levomethadyl
medicines for mental depression
medicines to control irregular heart rhythms
pimozide
pindolol
propranolol
risperidone
trimethobenzamide
ziprasidone
This medicine may also interact with the following medications:
barbiturates, like phenobarbital
diuretics
guanethidine
local and general anesthetics
phenytoin
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress.
You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
abnormal production of milk in females
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blurred vision
breast enlargement in both males and females
breathing problems
chest pain, fast or irregular heartbeat
confusion, restlessness
dark yellow or brown urine
dizziness or fainting spells
drooling, shaking
fever, chills, sore throat
involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs
seizures
stomach area pain
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
difficulty passing urine
difficulty sleeping
headache
sexual dysfunction
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Trifluoperazine Hydrochloride Solution for injection
What is this medicine?
TRIFLUOPERAZINE (trye floo oh PER a zeen) is used to treat schizophrenia. This medicine may also be used for the short-term treatment of anxiety.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood disorders or disease
dementia
head injury or coma
liver disease
Parkinson's disease
uncontrollable movement disorder
an unusual or allergic reaction to trifluoperazine, other medicines foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
amoxapine
certain antibiotics like gatifloxacin, grepafloxacin, sparfloxacin
cisapride
clozapine
droperidol
ephedrine
kaolin; pectin
levomethadyl
medicines to control irregular heart rhythms
medicines for mental depression
phenylpropanolamine
pimozide
pindolol
propranolol
risperidone
trimethobenzamide
ziprasidone
This medicine may also interact with the following medications:
barbiturates, like phenobarbital
diuretics
guanethidine
local and general anesthetics
phenytoin
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
abnormal production of milk in females
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blurred vision
breast enlargement in both males and females
breathing problems
chest pain, fast or irregular heartbeat
confusion, restlessness
dark yellow or brown urine
dizziness or fainting spells
drooling, shaking
fever, chills, sore throat
involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs
seizures
stomach area pain
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
difficulty passing urine
difficulty sleeping
headache
sexual dysfunction
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert