Tobramycin Inhalation powder, capsule

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat or prevent certain kinds of bacterial infections in the lungs. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• balance problems

• hearing problems

• kidney disease

• myasthenia gravis

• Parkinson's disease

• an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for inhalation. You breathe this medicine in through your mouth and into your lungs. You will be taught how to take this medicine. Follow the directions on your prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

You will get an information sheet with each prescription and refill. Read this sheet carefully each time. This sheet may change.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Take your doses at least 6 hours apart. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• cidofovir

• cisplatin

• colistin

• ethacrynic acid

• furosemide

• mannitol

• other aminoglycoside antibiotics

• polymyxin

• urea

• vancomycin

• viomycin

This medicine may also interact with the following medications:

• birth control pills

• diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional as directed. Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• change in amount or color of urine

• change in hearing

• dizziness

• fever or infection

• loss of balance

• redness, blistering, peeling or loosening of the skin, including inside the mouth

• unusual bleeding or bruising

• unusually weak or tired

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

• diarrhea

• changes in voice

• cough

• headache

• nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Tobramycin Nebulizer solution

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat or prevent certain kinds of bacterial infections in the lungs. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• balance problems

• hearing problems

• kidney disease

• myasthenia gravis

• Parkinson's disease

• an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. You will be taught how to use your nebulizer. Follow the directions on your prescription label. Do not use more often than directed.

You will get an information sheet with each prescription and refill. Read this sheet carefully each time. This sheet may change.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Take your doses at least 6 hours apart. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• cidofovir

• cisplatin

• colistin

• ethacrynic acid

• furosemide

• mannitol

• other aminoglycoside antibiotics

• polymyxin

• urea

• vancomycin

• viomycin

This medicine may also interact with the following medications:

• birth control pills

• diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional as directed. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• change in amount or color of urine

• change in hearing

• dizziness

• fever or infection

• loss of balance

• redness, blistering, peeling or loosening of the skin, including inside the mouth

• unusual bleeding or bruising

• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea

• changes in voice

• cough

• headache

• nausea, vomiting

• runny nose

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). You can also store this medicine at room temperature, up to 25 degrees C (77 degrees F) and throw away any unused medicine after 28 days. Protect from light. Do not use if the medicine is cloudy. Throw away any unused medicine after the expiration date.

Tobramycin Ophthalmic drops, solution

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat bacterial eye infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• wear contact lenses

• an unusual or allergic reaction to tobramycin or other antibiotics, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Try not to touch the tip of the dropper to anything, even your eye or fingertips. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Squeeze the prescribed number of drops into the pouch. Close the eye gently. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other eye products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better within a few days.

This medicine can make certain eye conditions worse. Only use it for conditions for which your doctor or health care professional has prescribed.

To prevent the spread of infection, do not share eye products, towels and washcloths with anyone else.

Do not wear contact lenses while you have any signs or symptoms of an eye infection. Ask your doctor or health care professional when you can start wearing your lenses again.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• burning, stinging or swelling of the eyelids

• increased flow of tears

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision

• eye irritation, itching

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store between 8 and 27 degrees C (46 and 80 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.

Tobramycin Ophthalmic ointment

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat bacterial eye infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• wear contact lenses

• an unusual or allergic reaction to tobramycin or other antibiotics, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the tube, to your eye, fingertips, or other surface. Squeeze the end of the tube to apply a thin layer of the ointment to the inside of the lower eyelid. Close the eye gently to spread the ointment. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other eye products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better within a few days.

A burning or stinging reaction that does not go away may mean you are allergic to this product. Stop using and call your doctor or health care professional.

This medicine can make certain eye conditions worse. Only use it for conditions for which your doctor or health care professional has prescribed.

To prevent the spread of infection, do not share eye products, towels and washcloths with anyone else.

You should not wear contact lenses while you have signs and symptoms of an eye infection. Ask your doctor or health care professional when you can wear your contact lenses again.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• burning, stinging or swelling of the eyelids

• increased flow of tears

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision

• eye irritation, itching

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store between 8 and 27 degrees C (46 and 80 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.

Tobramycin Sulfate Nebulizer solution

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat or prevent certain kinds of bacterial infections in the lungs. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• balance problems

• hearing problems

• kidney disease

• myasthenia gravis

• Parkinson's disease

• an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. You will be taught how to use your nebulizer. Follow the directions on your prescription label. Do not use more often than directed.

You will get an information sheet with each prescription and refill. Read this sheet carefully each time. This sheet may change.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Take your doses at least 6 hours apart. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• cidofovir

• cisplatin

• colistin

• ethacrynic acid

• furosemide

• mannitol

• other aminoglycoside antibiotics

• polymyxin

• urea

• vancomycin

• viomycin

This medicine may also interact with the following medications:

• birth control pills

• diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional as directed. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• change in amount or color of urine

• change in hearing

• dizziness

• fever or infection

• loss of balance

• redness, blistering, peeling or loosening of the skin, including inside the mouth

• unusual bleeding or bruising

• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea

• changes in voice

• cough

• headache

• nausea, vomiting

• runny nose

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). You can also store this medicine at room temperature, up to 25 degrees C (77 degrees F) and throw away any unused medicine after 28 days. Protect from light. Do not use if the medicine is cloudy. Throw away any unused medicine after the expiration date.

Tobramycin Sulfate Solution for injection

What is this medicine?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• balance problems

• cystic fibrosis

• hearing problems

• kidney disease

• myasthenia gravis

• Parkinson's disease

• an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle or infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• cidofovir

This medicine may also interact with the following medications:

• birth control pills

• cisplatin

• colistin

• diuretics

• medicines used during surgery for sleep or muscle relaxation

• other antibiotics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve or if you get new symptoms.

Tell your doctor or health care professional if you have any hearing problems, or problems passing urine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• burning, numbness, tingling

• change in amount or color of urine

• changes in hearing

• confused, dizzy, disoriented

• fever

• loss of balance

• muscle twitching, seizures

• redness, blistering, peeling or loosening of the skin, including inside the mouth

• unusual bleeding or bruising

• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea

• headache

• nausea, vomiting

• pain at site where injected

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.