Tiotropium; Olodaterol respiratory inhalation spray
Tiotropium; Olodaterol respiratory inhalation spray
What is this medicine?
TIOTROPIUM; OLODATEROL (tee oh TRO pee um; OH loe DA ter ol) inhalation is a combination of two medicines that help to open up the airways of your lungs. It is for chronic obstructive pulmonary disease (COPD), including chronic bronchitis or emphysema. Do NOT use for asthma or an acute asthma attack. Do NOT use for a COPD attack.
How should I use this medicine?
This medicine is inhaled through the mouth. It is used once per day. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice. Make sure that you are using your inhaler correctly. Ask you doctor or health care provider if you have any questions.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
breathing problems right after inhaling your medicine
changes in vision
chest pain
difficulty breathing or wheezing that increases or does not go away
fast, irregular heartbeat
feeling faint or lightheaded, falls
general ill feeling or flu-like symptoms
stomach pain
trouble passing urine or change in the amount of urine
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
back pain
constipation
cough
dry mouth
nervousness
runny nose
sore throat
tremor
What may interact with this medicine?
Do not take this medicine with any of the following medications:
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
atropine
certain medicines for allergy, cough and cold
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
diuretics
ipratropium
medicines for depression, anxiety, or psychotic disturbances
medicines for fungal infections like ketoconazole
medicines for weight loss including some herbal products
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
procarbazine
ritonavir
some antibiotics like clarithromycin, erythromycin, levofloxacin, linezolid, and telithromycin
some heart medicines
steroid medicines like prednisone or cortisone
stimulant medicines for attention disorders, weight loss, or to stay awake
theophylline
thyroid hormones
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose and continue with your regular schedule. Do not use double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. The inhaler should be discarded after 3 months or when the inhaler becomes locked, whichever comes first. Throw away any unopened packages after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
asthma
bladder problems or difficulty passing urine
diabetes
glaucoma
heart disease or irregular heartbeat
high blood pressure
kidney disease
pheochromocytoma
prostate disease
seizures
thyroid disease
an unusual or allergic reaction to tiotropium, olodaterol, ipratropium, atropine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checkups. Tell your doctor or health care professional if your symptoms do not get better.
If your symptoms get worse or if you need your short-acting inhalers more often, call your doctor right away. Do not use this medicine more than once every 24 hours.
Do not get the this medicine in your eyes. It can cause irritation, pain, or blurred vision.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Clean the inhaler as directed in the patient information sheet that comes with this medicine.
Updated:  
June 07, 2019