March 21, 2017

Spectinomycin injection

What is spectinomycin injection?

SPECTINOMYCIN (Trobicin®) is an antibiotic. It treats and cures gonorrhea (a type of sexually transmitted or venereal disease). Generic spectinomycin is not available.

NOTE: This drug is discontinued in the United States.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • syphilis - you need to be tested for syphilis before treatment with spectinomycin is started

  • an unusual or allergic reaction to spectinomycin or other antibiotics, other medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Spectinomycin is for injection into a muscle.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

Spectinomycin is usually given as a single dose. If you do need more than one dose it is important not to miss your appointment. If you miss a dose, get it as soon as you can.

What drug(s) may interact with spectinomycin?

There are no interactions known.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking spectinomycin?

Tell your prescriber or health care professional if your symptoms do not improve in a few days.

Anyone you have had sex with needs treatment for gonorrhea. Use a condom to stop reinfection of either you or your sexual partner.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how spectinomycin affects you.

What side effects may I notice from receiving spectinomycin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • fever or chills

  • dizziness

  • skin rash, itching

Minor side effects include:

  • irritation or pain at the injection site

  • nausea, vomiting

  • sleeplessness

  • reduced urine output

Where can I keep my medicine?

Keep out of the reach of children.

Store the dry powder at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze the diluent. After dissolving the powder, keep injection solution at room temperature between 15 and 30 degrees C (59 and 86 degrees F), and use within 24 hours. Throw away any unused injection solution.


March 21, 2017


U.S. FDA-approved Package Insert