Sodium Nitrite

March 21, 2017

Sodium Nitrite injection

What is Sodium Nitrite injection?

SODIUM NITRITE injection is used to treat cyanide poisoning. It is used with two other medications, amyl nitrite and sodium thiosulfate.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • carbon monoxide poisoning or smoke inhalation

  • heart problems

  • kidney or liver problems

  • low blood pressure

  • methemoglobinemia

  • vision problems

  • an unusual or allergic reaction to Sodium Nitrite, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should this medicine be used?

This medicine is injected into a vein. It is usually given by a health-care professional or other trained person. Follow all instructions for use exactly.

What if I miss a dose?

This does not apply.

What drug(s) may interact with Sodium Nitrite?

Do not take this medicine with any of the following medications:

  • sildenafil

  • tadalafil

  • vardenafil

This medicine may also interact with the following medications:

  • medicines for high blood pressure

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Sodium Nitrite?

Your condition will be closely monitored while receiving this medicine.

What side effects may I notice from receiving Sodium Nitrite?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blue finger nails or lips

  • fast heart beat

  • fast or difficult breathing

  • vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • dizziness

  • flushing

  • headache

  • nausea

  • restlessness

Where can I keep my medicine?

Keep out of the reach of children.

Store below 25 degrees C (77 degrees F). Protect from light and moisture. Throw away any unused portion after opening the ampules or vials. Discard after expiration date.


March 21, 2017


U.S. FDA-approved Package Insert