Sipuleucel-T injection

What is this medicine?

SIPULEUCEL-T (SI pu LOO sel - tee) is a vaccine for the treatment of prostate cancer. It is made from cells in your immune system.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting. This medicine is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before each infusion of this medicine. Your collected cells are then sent to a special center where they are mixed with a protein to get them ready for your infusion.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• chest pain or palpitations

• dizziness

• fast,irregular heartbeat

• fever

• nausea, vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• back pain

• fatigue

• headache

• joint pain

What may interact with this medicine?

• medicines that suppress your immune system like some medicines for cancer

• steroid medicines like prednisone or cortisone

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment. If you miss an appointment for your infusion of this medicine, your dose will not be able to be used.

Where should I keep my medicine?

This drug is only given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• heart disease

• lung or breathing disease, like asthma

• an unusual or allergic reaction to sipuleucel-T, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Report any side effects that you notice during your treatment right away, such as changes in your breathing, fever, or chills. These may also occur after your infusion.

Tell your doctor or health care professional if you have any other reaction or unusual symptom after getting this medicine.