Typhoid Vaccine, Live oral enteric-coated capsules

What is this medicine?

TYPHOID ORAL VACCINE (TYE foid vax EEN) is used to prevent typhoid infection. The vaccine is recommended if you travel to parts of the world where typhoid is common.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Take this medicine on an empty stomach, at least 1 hour before food. Do not take with food. Do not cut, crush or chew this medicine.

A copy of Vaccine Information Statements will be given before each vaccination. Read this sheet carefully each time. The sheet may change frequently.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea

• fever

• headache

• nausea, vomiting

• stomach pain

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• certain antibiotics like sulfamethoxazole (SMZ) or other sulfonamides

This medicine may also interact with the following medications:

• antimalarial drugs

• immune globulins

• medicines for organ transplant

• medicines to treat cancer

• other vaccines

• some medicines for arthritis

• steroid medicines like prednisone or cortisone

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you miss a dose. Four doses, given 2 days apart, are needed for protection. The last dose should be given at least 1 week before travel to allow the vaccine time to work.

Where should I keep my medicine?

Keep out of the reach of children.

Store refrigerated between 2 and 8 degrees C (35.6 and 46.4 degrees F). Do not freeze. Keep this vaccine in the original container.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• active infection with fever

• cancer

• HIV or AIDS

• immune system problems

• low blood counts, like low white cell, platelet, or red cell counts

• recent or ongoing radiation therapy

• stomach or intestine problems

• an unusual or allergic reaction to vaccines, yeast, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

This vaccine, like all vaccines, may not fully protect everyone.

Report any side effects that are worrisome to your doctor right away.