Rotigotine Transdermal Patch - 24 hour

What is this medicine?

ROTIGOTINE (roe TIG oh teen) is used to control the signs and symptoms of Parkinson's disease or restless legs syndrome.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• asthma

• heart disease

• high blood pressure

• sleep disorder

• mental illness

• an unusual or allergic reaction to rotigotine, sulfites, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for external use only. Follow the directions on the prescription label. Use exactly as directed. Wash hands after removing and applying this medicine. Change the patch each day at the same time. Apply the patch to an area of the upper arm or body that is clean, dry, and hairless. Do not use this patch on skin that is injured, irritated, oily, or calloused. Do not apply where the patch will be rubbed by tight clothing or a waistband. Do not apply to the same place more than once every 14 days in order to prevent skin irritation. Do not cut or trim the patch. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Always remove the old patch before you apply a new one. Remove patch slowly and carefully to avoid irritation. After removal, fold the patch so that it sticks to itself and throw it away. After removal of patch, wash the area with soap and water to remove any drug or adhesive. Baby oil or mineral oil may be used if needed. Do not use alcohol or other liquids.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

• alcohol

• droperidol

• haloperidol

• loxapine

• medicines for anxiety or sleep

• metoclopramide

• memantine

• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

• pimozide

• thiothixene

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.

There have been reports of increased sexual urges or other strong urges such as gambling while taking this medicine. If you experience any of these while taking this medicine, you should report this to your health care provider as soon as possible.

Heating this patch may change the amount of this medicine that you get from the patch. Avoid exposing the patch to heating pads, electric blankets, heat lamps, saunas, hot tubs, and heated water beds. Do not wear this patch on skin that gets hot from direct sunlight.

If you are going to have a magnetic resonance imaging (MRI) procedure, tell your MRI technician if you have this patch on your body. It must be removed before a MRI.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• anxiety, restlessness

• breathing problems

• confusion

• dizziness

• falling asleep during normal activities like driving

• fast, irregular or slow heartbeat

• feeling faint or lightheaded, falls

• hallucination, loss of contact with reality

• skin irritation, redness, or swelling

• uncontrollable head, mouth, neck, arm, or leg movements

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• constipation

• difficulty sleeping

• headache

• loss of appetite

• nausea, vomiting

• stomach pain

• weight gain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Store in original pouch until just before use. Throw away any unused medicine after the expiration date.