Romiplostim injection

What is this medicine?

ROMIPLOSTIM (roe mi PLOE stim) helps your body make more platelets. This medicine is used to treat low platelets caused by chronic idiopathic thrombocytopenic purpura (ITP).

How should I use this medicine?

This medicine is for injection under the skin. It is given by a health care professional in a hospital or clinic setting.

A special MedGuide will be given to you before your injection. Read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose

• signs and symptoms of a blood clot such as chest pain; shortness of breath; pain, swelling, or warmth in the leg

• signs and symptoms of a stroke like changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• headache

• pain in arms and legs

• pain in mouth

• stomach pain

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• bleeding disorders

• bone marrow problem, like blood cancer or myelodysplastic syndrome

• history of blood clots

• liver disease

• surgery to remove your spleen

• an unusual or allergic reaction to romiplostim, mannitol, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

Visit your prescriber or health care professional for regular checks on your progress and for the needed blood tests. It is important to keep all appointments.