Rivaroxaban oral tablets
Rivaroxaban oral tablets
What is this medicine?
RIVAROXABAN (ri va ROX a ban) is an anticoagulant (blood thinner). It is used to treat blood clots in the lungs or in the veins. It is also used to prevent blood clots in the lungs or in the veins. It is also used to lower the chance of stroke in people with a medical condition called atrial fibrillation.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. Stopping this medicine may increase your risk of a blood clot. Be sure to refill your prescription before you run out of medicine.
If you are taking this medicine after hip or knee replacement surgery, take it with or without food. If you are taking this medicine for atrial fibrillation, take it with your evening meal. If you are taking this medicine to treat blood clots, take it with food at the same time each day. If you are unable to swallow your tablet, you may crush the tablet and mix it in applesauce. Then, immediately eat the applesauce. You should eat more food right after you eat the applesauce containing the crushed tablet.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
back pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose
signs and symptoms of a blood clot such as chest pain; shortness of breath; pain, swelling, or warmth in the leg
signs and symptoms of a stroke such as changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of coordination
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dizziness
muscle pain
What may interact with this medicine?
Do not take this medicine with any of the following medications:
defibrotide
This medicine may also interact with the following medications:
aspirin and aspirin-like medicines
certain antibiotics like erythromycin, azithromycin, and clarithromycin
certain medicines for fungal infections like ketoconazole and itraconazole
certain medicines for irregular heart beat like amiodarone, quinidine, dronedarone
certain medicines for seizures like carbamazepine, phenytoin
certain medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
conivaptan
felodipine
indinavir
lopinavir; ritonavir
NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
ranolazine
rifampin
ritonavir
SNRIs, medicines for depression, like desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
SSRIs, medicines for depression, like citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline
St. John's wort
verapamil
What if I miss a dose?
If you take your medicine once a day and miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
If you take your medicine twice a day and miss a dose, take the missed dose immediately. In this instance, 2 tablets may be taken at the same time. The next day you should take 1 tablet twice a day as directed.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
antiphospholipid antibody syndrome
artificial heart valve
bleeding disorders
bleeding in the brain
blood in your stools (black or tarry stools) or if you have blood in your vomit
history of blood clots
history of stomach bleeding
kidney disease
liver disease
low blood counts, like low white cell, platelet, or red cell counts
recent or planned spinal or epidural procedure
take medicines that treat or prevent blood clots
an unusual or allergic reaction to rivaroxaban, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your healthcare professional for regular checks on your progress. You may need blood work done while you are taking this medicine. Your condition will be monitored carefully while you are receiving this medicine. It is important not to miss any appointments.
Avoid sports and activities that might cause injury while you are using this medicine. Severe falls or injuries can cause unseen bleeding. Be careful when using sharp tools or knives. Consider using an electric razor. Take special care brushing or flossing your teeth. Report any injuries, bruising, or red spots on the skin to your healthcare professional.
If you are going to need surgery or other procedure, tell your healthcare professional that you are taking this medicine.
Wear a medical ID bracelet or chain. Carry a card that describes your disease and details of your medicine and dosage times.
Updated:  
March 21, 2020