Remifentanil
Remifentanil injection
What is Remifentanil injection?
REMIFENTANIL (Ultiva®) helps to induce and maintain anesthesia and sedation during and after surgery or other procedures. An anesthesiologist or specially trained health care professional will give remifentanil to you. Generic remifentanil injections are not available.
What should my health care professional know before I receive Remifentanil?
They need to know if you have any of these conditions:
an infection
heart disease
high or low blood pressure
intestinal disease
kidney disease
liver disease
lung disease or breathing difficulties
seizure disorder
an allergic or unusual reaction to remifentanil, alfentanil, sufentanil, meperidine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should this medicine be used?
Remifentanil is for infusion into a vein. It is given by a specially trained health care professional in a hospital or clinic setting.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
This does not apply.
What drug(s) may interact with Remifentanil?
alcohol
dronabinol
medicines for depression (examples: MAOIs, nefazodone, fluoxetine, fluvoxamine, or sertraline)
medicines for high blood pressure
medicines for psychiatric disorders
medicines for seizures
medicines for sleep
prescription medicines for pain
St. John's wort or any herbal preparations containing St. John's wort
Tell your prescriber or health care professional about all other medicines you that are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also, tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking Remifentanil?
Remifentanil is used mostly during surgery or while you are recovering from surgery. Tell your prescriber or health care professional if you continue to have pain or if you have new or different type of pain.
Make sure to tell your anesthesiologist or other health care professional if you are taking any herbal products. Ideally, you should stop taking any herbal products at least 2—3 weeks before your surgery to decrease the risk of any side effects. Some products may increase the effects of remifentanil.
What side effects may I notice from receiving Remifentanil?
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
breathing difficulties, wheezing
cold, clammy skin
seizures
slow or fast heartbeat
skin rash
unusual weakness
More common:
confusion
lightheadedness or fainting spells
decrease or difficulty passing urine
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
blurred vision
clumsiness, unsteadiness
constipation
dizziness, drowsiness
dry mouth
flushing
headache
itching
nausea/vomiting
Where can I keep my medicine?
This does not apply. You will only receive remifentanil in a hospital or clinic setting. You will not receive remifentanil at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert