Pramipexole oral extended-release tablet
What is this medicine?
PRAMIPEXOLE (pra mi PEX ole) is used to treat symptoms of Parkinson's disease.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause side effects or your condition may worsen.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in emotions or moods
changes in vision
falling asleep during normal activities like driving
hallucination, loss of contact with reality
involuntary muscle contractions; difficulty swallowing; difficulty walking
new or increased gambling urges, sexual urges, uncontrolled spending, binge or compulsive eating, or other urges
new or worsening curve in the spine
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded; falls; unusually weak or tired
uncontrollable movements of the arms, face, head, mouth, neck, or upper body
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
antihistamines for allergy, cough and cold
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for seizures like phenobarbital, primidone
certain medicines for sleep
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
medicines for blood pressure
medicines that relax muscles for surgery
narcotic medicines for pain
What if I miss a dose?
If you miss a dose, skip the dose you missed. Take the next dose at your regular time. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) . Protect from moisture. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
dizziness or fainting spells
feel sleepy or have fallen asleep suddenly during the day
have trouble controlling your muscles (dyskinesia)
if you often drink alcohol
low blood pressure
an unusual or allergic reaction to pramipexole, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. It may be several weeks or months before you feel the full effect of this medicine. Continue to take your medicine on a regular schedule.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your health care provider if the problem does not go away or is severe.
There have been reports of increased sexual urges or other strong urges such as gambling while taking some medicines for Parkinson's disease. If you experience any of these urges while taking this medicine, you should report it to your health care provider as soon as possible.
Talk with your doctor if you have posture changes you cannot control. These may include your neck bending forward, your spine bending forward at the waist, or tilting sideways when you sit, stand, or walk.
Some patients notice a tablet residue, which may resemble a tablet or pieces of a tablet, in their stool. If this occurs, contact your health care provider. Your medication may need to be changed. Do not stop your medicine except on the advice of your health care provider.
July 17, 2018