Podophyllum resin topical solution

What is this medicine?

PODOPHYLLUM (Poe-DOF-il-um) is used to treat external genital warts.

How should I use this medicine?

This medicine is for external use only. It is given by a health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• muscle pain

• pain, tingling, numbness in the hands or feet

• stomach pain

• unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• skin irritation at site of use

What may interact with this medicine?

Interactions are not expected. Do not use any other skin products on the same area of skin without asking your doctor or health care professional.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• diabetes

• peripheral vascular disease

• skin conditions or sensitivity

• an unusual or allergic reaction to podophyllum, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Females should receive regular pelvic exams while being treated for genital warts. Most patients see improvement within 4 weeks. It may take up to 16 weeks to see a full clearing of the warts. This medicine is not a cure. New warts may develop during or after treatment. The only way to prevent infecting others with the HPV virus (the virus that causes genital warts) is to avoid direct skin-to-skin contact. If warts are visible in the genital area, sexual contact should be avoided until the warts are treated. The use of latex condoms during sexual contact may reduce, but not entirely prevent, infecting others.

If you're a woman, do not get pregnant for at least 2 months after your last dose. If you do get pregnant, tell your doctor.