Pimozide
Pimozide Oral tablet
What is this medicine?
PIMOZIDE (PI moe zide) helps to reduce the muscle and speech tics that are caused by Tourette's syndrome.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
dementia
heart disease
kidney disease
liver disease
Parkinson's disease
an unusual or allergic reaction to pimozide, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
antiviral medicines for HIV or AIDS
aprepitant
arsenic trioxide
certain antibiotics like ciprofloxacin, clarithromycin, dalfopristin; quinupristin, erythromycin, isoniazid, gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, telithromycin
certain medicines for ADHD like amphetamine, dexmethylphenidate, dextroamphetamine, methylphenidate
certain medicines for depression, anxiety, or psychotic disturbances like citalopram, clozapine, escitalopram, haloperidol, maprotiline, paroxetine, sertraline, fluvoxamine, nefazodone, ziprasidone
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like dofetilide, dronedarone
chloroquine
cimetidine
cisapride
conivaptan
cyclobenzaprine
diltiazem
droperidol
grapefruit juice
halothane
imatinib
local anesthetics
methadone
mifepristone
nicardipine
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
quinine
ranolazine
sodium phosphates
tacrolimus
vardenafil
verapamil
zafirlukast
zileuton
This medicine may also interact with the following medications:
barbiturates like phenobarbital
bosentan
certain medicines for anxiety or sleep
certain medicines for asthma
certain medicines for seizures like carbamazepine
levodopa
narcotic medicines for pain
rifampin
tacrine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Do not stop taking this medicine suddenly. You may need to gradually reduce the dose. Only stop taking this medicine on advice of your doctor or health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks.
Do not drink grapefruit juice products while taking this medicine. This can increase the chance of developing serious heart problems.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
change in emotion or behavior such as feeling depressed, angry, or anxious
fast, slow or irregular heartbeat
fever or chills, sore throat
inability to control muscle movements in the face, hands, arms, or legs
loss of balance or difficulty walking
seizures
spasms of the face, tongue, or mouth
tremors or trembling
uncontrollable tongue or mouth movements
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dizziness; especially on standing from a sitting or lying position
drowsiness
dry mouth
sexual difficulties
weight loss
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert