Phenytoin injection
Phenytoin injection
What is this medicine?
PHENYTOIN (FEN i toyn) is used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery.
How should I use this medicine?
This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain or tightness
confusion
dark yellow or brown urine
fast or irregular heartbeat
fever, sore throat
headache
loss of seizure control
poor control of body movements or difficulty walking
redness, blistering, peeling or loosening of the skin, including inside the mouth
unusual bleeding or bruising, pinpoint red spots on skin
vomiting
worsening of mood, thoughts or actions of suicide or dying
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation
difficulty sleeping
excessive hair growth on the face or body
nausea
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines used to treat HIV infection or AIDS that are given in combination with cobicistat
delavirdine
ibrutinib
ranolazine
This medicine may also interact with the following medications:
albendazole
alcohol
- aspirin and aspirin-like medicines
certain medicines for blood pressure like nifedipine, nimodipine, and verapamil
certain medicines for cancer
certain medicines for cholesterol like atorvastatin, simvastatin, and fluvastatin
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for fungal infections like ketoconazole and itraconazole
certain medicines for irregular heart beat like amiodarone and quinidine
certain medicines for seizures like carbamazepine, phenobarbital, and topiramate
certain medicines for stomach problems like cimetidine and omeprazole
chloramphenicol
cyclosporine
diazoxide
digoxin
disulfiram
doxycycline
female hormones, like estrogens and birth control pills
furosemide
halothane
isoniazid
medicines that relax muscles for surgery
medicines used to treat HIV infection or AIDS
methylphenidate
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
praziquantel
reserpine
rifampin
St. John's Wort
steroid medicines like prednisone or cortisone
sulfonamides like sulfamethoxazole or sulfasalazine
supplements like folic acid or vitamin D
theophylline
ticlopidine
tolbutamide
warfarin
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an alcohol abuse problem
Asian ancestry
diabetes
heart problems
liver disease
low blood pressure
suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
an unusual or allergic reaction to phenytoin, hydantoin or other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine. Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.
Updated:  
July 17, 2018