Pentoxifylline extended-release tablets

What is this medicine?

PENTOXIFYLLINE (pen tox I fi leen) improves blood flow. This medicine helps to decrease the pain, discomfort, or cramps you can get from having poor circulation in your legs.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole. Do not crush or chew. Take with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• agitation

• chest pain, fast or irregular heartbeat

• flushing

• seizures

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• dizziness or drowsiness

• headache

• indigestion

• nausea, vomiting

What may interact with this medicine?

• medicines for blood pressure

• theophylline

• warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• kidney or liver disease

• previous bleeding in the head or retina

• an unusual or allergic reaction to pentoxifylline, caffeine, theophylline, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You may feel some benefit after 2 to 4 weeks of treatment, but it can take up to 8 weeks before you get the full benefit.

Smoking tobacco or marijuana can make your condition worse by further narrowing the blood vessels. Do not smoke.