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What is this medicine?
Orlistat (OR li stat) is used to help people lose weight and maintain weight loss while eating a reduced-calorie diet. This medicine decreases the amount of fat that is absorbed from your diet.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription or product label. Take this medicine with each main meal that contains about 30 percent of the calories from fat or within 1 hour after each meal. Do not take your medicine more often than directed. If you occasionally miss a meal or have a meal without fat, you can skip that dose of this medicine.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply. Use of this medicine without a prescription is not approved in children less than 18 years.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
bloody or black, tarry stools
signs and symptoms of kidney stones like blood in the urine; pain in the lower back or side; pain when urinating
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
trouble passing urine or change in the amount of urine
uncontrolled, urgent bowel movements
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
increased number of bowel movements
oily stools (bowel movements may be clear, orange or brown in color)
What may interact with this medicine?
certain antivirals for HIV or hepatitis
certain medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, apixaban, dabigatran, edoxaban, and rivaroxaban
medicines for diabetes
medicines for seizures
other medicines or herbal and dietary supplements for weight loss
supplements like vitamins A, beta-carotene, D, E and K
What if I miss a dose?
If you miss a dose, take it within 1 hour following the meal that contains fat. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you occasionally miss a meal or have a meal without fat, you can skip that dose of this medicine.
Where should I keep my medicine?
Keep out of the reach of children.
Storage at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an eating disorder, such as anorexia or bulimia
history of irregular heart beat
HIV or AIDS
liver disease or hepatitis
problems absorbing food
stomach or intestine problems
take medicines that treat or prevent blood clots
an unusual or allergic reaction to orlistat, other medicines, foods, dyes, supplements or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your health care professional for regular checks on your progress.
This medicine can cause decreased absorption of some vitamins. You should take a daily multivitamin that contains normal amounts of vitamins D, E, K and beta-carotene or vitamin A. Take the multivitamin once per day at bedtime unless otherwise directed by your doctor or healthcare professional. Discuss the foods you eat and the vitamins you take with your health care professional.
You should use this medicine with a reduced-calorie diet that contains no more than about 30 percent of the calories from fat. Divide your daily intake of fat, carbohydrates, and protein evenly over your 3 main meals. Follow a well-balanced, reduced-calorie, low fat diet. Try starting this diet before taking this medicine. Following a low fat diet can help reduce the possible side effects from this medicine.
Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. Losing weight while pregnant is not advised and may cause harm to the unborn child. Talk to your health care provider for more information.
Do not use this medicine if you have had an organ transplant. This medicine interferes with some medicines used to prevent transplant rejection.
October 27, 2020