Nivolumab injection
Nivolumab injection
What is this medicine?
NIVOLUMAB (nye VOL ue mab) is a monoclonal antibody. It is used to treat melanoma, lung cancer, kidney cancer, head and neck cancer, Hodgkin lymphoma, urothelial cancer, colon cancer, esophageal cancer, and liver cancer.
How should I use this medicine?
This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
blood in the urine
bloody or watery diarrhea or black, tarry stools
changes in emotions or moods
changes in vision
chest pain
cough
dizziness
feeling faint or lightheaded, falls
fever, chills
headache with fever, neck stiffness, confusion, loss of memory, sensitivity to light, hallucination, loss of contact with reality, or seizures
joint pain
mouth sores
redness, blistering, peeling or loosening of the skin, including inside the mouth
severe muscle pain or weakness
signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger or thirst; increased urination
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
swelling of the ankles, feet, hands
trouble passing urine or change in the amount of urine
unusually weak or tired
weight gain or loss
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
bone pain
constipation
decreased appetite
diarrhea
muscle pain
nausea, vomiting
tiredness
What may interact with this medicine?
Interactions have not been studied.
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What if I miss a dose?
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
immune system problems
kidney disease
liver disease
lung disease
organ transplant
stomach or intestine problems
thyroid disease
an unusual or allergic reaction to nivolumab, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
This drug may make you feel generally unwell. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 5 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 5 months after stopping it.
Updated:  
June 17, 2020