Muromonab-CD3
Muromonab-CD3 Solution for injection
What is this medicine?
MUROMONAB-CD3 (myoo roe MOE nab CD3) is used to treat rejection of a kidney transplant.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
angina
fever
fluid overload, sudden weight gain
heart disease
high blood pressure
lung disease
previous treatment with muromonab
seizure condition
an unusual or allergic reaction to muromonab, murine, mice, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
azathioprine
cyclosporine
hormones such as prednisone or cortisone
indomethacin
some vaccines
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine. You will need regular blood work while you are taking this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
This medicine may decrease your body's ability to fight infection. Avoid being around people who are sick. Do not get any vaccinations without your doctor's approval.
This medicine may increase your risk of getting cancer. Talk to your doctor about the benefits and risks of taking this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
bruising, pinpoint red spots on the skin
chest pain
confusion
extreme changes in behavior or mood
eyes sensitive to light
fast, irregular heartbeat
fever, chills, or any other sign of infection
pain, tingling, numbness in the hands or feet
seizures
stiff neck
swelling of the ankles, feet, hands
trouble passing urine or change in the amount of urine
unusually high or low blood pressure
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
dizziness
ear or nose congestion
headache
nausea, vomiting
pain, redness at site where injected
stomach upset
trembling
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert