Mepolizumab injection

July 17, 2018

Mepolizumab injection

What is this medicine?

MEPOLIZUMAB (me poe LIZ ue mab) is used in combination with other treatments to help treat severe asthma. It is also used for the treatment of a specific condition that causes inflammation of smaller blood vessels (vasculitis).

How should I use this medicine?

This medicine is for injection under the skin. It is give by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • painful rash or blisters

  • signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls

  • signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • headache

  • pain, redness, or irritation at the site where injected

  • weak or tired

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • parasitic (helminth) infection

  • an unusual or allergic reaction to mepolizumab, hamster proteins, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Talk with your doctor if you have not had chickenpox or the vaccine for chickenpox.

Do not stop taking your other asthma medicines unless instructed to do so by your doctor or health care professional.

Your condition will be monitored carefully while you are receiving this medicine.


July 17, 2018