Loxapine inhalation powder
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Loxapine inhalation powder
What is this medicine?
LOXAPINE (LOX a peen) inhaler is used to treat certain symptoms of schizophrenia and bipolar disorder. Bipolar disorder is also known as manic-depression.
How should I use this medicine?
This medicine is inhaled by mouth. It will only be given to you by a health care professional while you are in a hospital or clinic setting. Your healthcare professional will show you how to take this medicine right before you use it. Follow the instructions for use carefully.
A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest tightness
confusion
fever, chills, sore throat
palpitations
seizures
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
trouble passing urine or change in the amount of urine
trouble swallowing
uncontrollable movements of the arms, face, head, mouth, neck, or upper body
unusual bruising or bleeding
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste (bad, bitter, or metallic taste)
constipation
drowsiness
dry mouth
sore throat
What may interact with this medicine?
Do not take this medicine with any of the following medications:
metoclopramide
This medicine may also interact with the following medications:
alcohol
antihistamines for allergy, cough, and cold
atropine
carbamazepine
certain medicines for anxiety or sleep
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
epinephrine
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
ipratropium
levodopa or other medicines for Parkinson's disease
lithium
medicines for blood pressure
medicines for seizures
medicines that relax muscles for surgery
narcotic medicines for pain
phenothiazines like chlorpromazine, prochlorperazine, thioridazine
What if I miss a dose?
This does not apply; this medicine is not for regular use.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
dementia
diabetes
difficulty swallowing
glaucoma
have trouble controlling your muscles
heart disease
if you often drink alcohol
liver disease
low blood counts, like low white cell, platelet, or red cell counts
low blood pressure
lung or breathing disease, like asthma
Parkinson's disease
prostate disease
seizures
trouble passing urine
an unusual or allergic reaction to loxapine, amoxapine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your health care professional if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medicine.
This medicine may cause breathing problems. Your healthcare provider will check you for breathing problems before and after you take this medicine. You will be observed closely for about 1 hour after you take this medicine. Tell your healthcare provider right away if you have wheezing, coughing, chest tightness, or shortness of breath at any time after taking this medicine. Breathing problems that occur after taking this medicine may require additional treatments.
You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine and make you more dizzy. Avoid alcoholic drinks.
This drug can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your health care provider right away.
Updated:  
November 15, 2020