Lopinavir; Ritonavir
Lopinavir, Ritonavir Oral capsule
What is this medicine?
LOPINAVIR; RITONAVIR (loe PIN a veer; ri TOE na veer) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
hemophilia
liver disease
an unusual or allergic reaction to lopinavir, ritonavir, other medicines, castor oil, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months old for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alfuzosin
certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
meperidine
midazolam
pimozide
ranolazine
red yeast rice
rifampin
rifapentine
St. John's wort
thioridazine
triazolam
ziprasidone
This medicine may also interact with the following medications:
atovaquone
birth control pills
bupropion
certain medicines for blood pressure like felodipine, nicardipine, nifedipine
certain medicines for cholesterol like atorvastatin
certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
certain medicines for irregular heart beat like amiodarone, bepridil, quinidine
certain medicines for seizures like carbamazepine, phenytoin
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
cyclosporine
dasatinib
dexamethasone
fentanyl
fluticasone
methadone
nilotinib
other medicines for HIV or AIDS
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
rapamycin
rifabutin
salmeterol
tacrolimus
trazodone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heart rate
feeling faint or lightheaded, falls
nausea, vomiting, abdominal pain
red, hot, painful spot on leg
redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
difficulty sleeping
headache
heartburn
increased hunger or thirst
increased urination
unusually weak or tired
weight gain around waist, back, or thinning of face, arms, legs
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Throw away any unused medicine after the expiration date. If stored at room temperature, up to 25 degrees C (77 degrees F), you must throw the medicine away after 2 months.
Lopinavir, Ritonavir Oral solution
What is this medicine?
LOPINAVIR; RITONAVIR (loe PIN a veer; ri TOE na veer) is two antiretroviral medicines in one tablet. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
hemophilia
liver disease
an unusual or allergic reaction to lopinavir, ritonavir, other medicines, castor oil, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Use a specially marked spoon or container to measure the dose. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for infants as young as 14 days old for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alfuzosin
certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
disulfiram
dofetilide
dronedarone
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
meperidine
metronidazole
midazolam
pimozide
ranolazine
red yeast rice
rifampin
rifapentine
St. John's wort
thioridazine
triazolam
ziprasidone
This medicine may also interact with the following medications:
atovaquone
birth control pills
bupropion
certain medicines for blood pressure like felodipine, nicardipine, nifedipine
certain medicines for cholesterol like atorvastatin
certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
certain medicines for irregular heart beat like amiodarone, bepridil, quinidine
certain medicines for seizures like carbamazepine, phenytoin
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
cyclosporine
dasatinib
dexamethasone
fentanyl
fluticasone
methadone
nilotinib
other medicines for HIV or AIDS
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
rapamycin
rifabutin
salmeterol
tacrolimus
trazodone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heart rate
feeling faint or lightheaded, falls
nausea, vomiting, abdominal pain
red, hot, painful spot on leg
redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
difficulty sleeping
headache
heartburn
increased hunger or thirst
increased urination
unusually weak or tired
weight gain around waist, back, or thinning of face, arms, legs
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Throw away any unused medicine after the expiration date. If stored at room temperature, up to 25 degrees C (77 degrees F), you must throw the medicine away after 2 months.
Lopinavir, Ritonavir Oral tablet
What is this medicine?
LOPINAVIR; RITONAVIR (loe PIN a veer; ri TOE na veer) is two antiretroviral medicines in one tablet. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
hemophilia
liver disease
an unusual or allergic reaction to lopinavir, ritonavir, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Do not crush, break, or chew the tablets. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months old for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alfuzosin
certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
meperidine
midazolam
pimozide
ranolazine
red yeast rice
rifampin
rifapentine
St. John's wort
thioridazine
triazolam
ziprasidone
This medicine may also interact with the following medications:
atovaquone
birth control pills
bupropion
certain medicines for blood pressure like felodipine, nicardipine, nifedipine
certain medicines for cholesterol like atorvastatin
certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
certain medicines for irregular heart beat like amiodarone, bepridil, quinidine
certain medicines for seizures like carbamazepine, phenytoin
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
cyclosporine
dasatinib
dexamethasone
fentanyl
fluticasone
methadone
nilotinib
other medicines for HIV or AIDS
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
rapamycin
rifabutin
salmeterol
tacrolimus
trazodone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heart rate
feeling faint or lightheaded, falls
nausea, vomiting, abdominal pain
red, hot, painful spot on leg
redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
difficulty sleeping
headache
heartburn
increased hunger or thirst
increased urination
unusually weak or tired
weight gain around waist, back, or thinning of face, arms, legs
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep in original container. Do not store this medicine outside the original container for longer than 2 weeks. Protect from moisture and humidity. Throw away any unused medicine after the expiration date.
Updated:
March 21, 2017
Sources:
U.S. FDA-approved Package Insert