Levobupivacaine
Levobupivacaine injection
What is levobupivacaine injection?
LEVOBUPIVACAINE (Chirocaine®) is a drug that is injected before and during various surgical procedures or during labor and delivery. Levobupivacaine is an anesthestic, and causes loss of feeling in the skin and surrounding tissues. Generic levobupivacaine is not available.
NOTE: This drug is discontinued in the US.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of the following conditions:
blood clotting problems
heart or blood vessel disease
infection
liver disease
myasthenia gravis
an unusual or allergic reaction to levobupivacaine, other local anesthetics, medicines, foods, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Levobupivacaine is injected into a specific area to make it numb before a surgery or other procedure. Depending on the type of procedure it may be given into the area around your spine or into other areas so you will not feel pain during the procedure. Only a specially trained health-care professional will give levobupivacaine in a hospital or clinic.
What if I miss a dose?
This does not apply.
What drug(s) may interact with levobupivacaine?
alcohol
bosentan
cimetidine
ciprofloxacin
clarithromycin
blood thinners such as warfarin
erythromycin
medicines to treat hypertension
medicines to treat fungal infections including fluconazole, itraconazole, and ketoconazole
medicines to treat seizures such as carbamazepine, phenobarbital, and phenytoin
medicines to treat depression
medicines used to help you sleep
medicines used to treat heart disease or chest pain such as isosorbide and nitroglycerin
medicines for myasthenia gravis
mecamylamine
rifabutin
rifampin
some medicines for pain
some medicines used to treat HIV-infections such as indinavir, ritonavir, and saquinavir
Tell your prescriber or health care professional about all other medicines that you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What do I need to watch for after I receive levobupivacaine?
Let your prescriber or health care professional know if the feeling of numbness does not wear off within a few hours of receiving the levobupivicaine dosage.
After an injection of levobupivacaine, the area will be numb for some time and you will not be aware of pain. Try to avoid injury to the area.
What side effects may I notice from receiving levobupivacaine?
Side effects that you should report to your prescriber or health care professional as soon as possible:
anxiety, restlessness
blurred vision
difficulty breathing
dizziness, drowsiness
fever
irregular heartbeat (palpitations)
nausea, vomiting
seizures (convulsions)
skin rash, hives
swelling of the face or mouth
tremors
If they are going to occur, these side effects may become apparent before you leave the hospital, clinic or dental office. Call your health care provider as soon as you can if you get any of the above reactions later.
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
constipation
headache
itching
numbness or tingling at the injection site or areas that were numb
pain at the injection site
Where can I keep my medicine?
You will only receive levobupivacaine in a hospital or clinic setting prior to surgery or other procedures. You will not need to take this medicine at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert