What is this medicine?
IVABRADINE (eye VAB ra deen) is used to reduce the risk of going to the hospital due to worsening heart failure.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Avoid grapefruit juice. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
high blood pressure
signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded; breathing problems
unusually slow heartbeat
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in vision
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like ketoconazole and itraconazole
certain antibiotics called macrolide antibiotics like clarithromycin and telithromycin
certain medicines for HIV disease called protease inhibitors like nelfinavir
This medicine may also interact with the following medications:
beta-blockers like metoprolol and propranolol
calcium channel blockers like diltiazem and verapamil
certain medicines for seizures like barbiturates and phenytoin
St. John's wort
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
certain heart conditions like sick sinus syndrome, sinoatrial block, or third degree atrioventricular block
heart failure that has recently worsened
low blood pressure (less than 90/50 mmHg)
low resting heart rate (less than 60 beats per minute)
an unusual or allergic reaction to ivabradine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.
You may experience changes in vision. Use caution if you are driving or using machinery when sudden changes in light intensity may occur, especially while driving at night. This effect may decrease after using this medicine for a long time.
Do not become pregnant while taking this medicine. Women who are able to get pregnant must use birth control while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
July 17, 2018