What is this medicine?
ITRACONAZOLE (i tra KO na zole) is an antifungal medicine. It is used to treat certain kinds of fungal or yeast infections.
How should I use this medicine?
This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in hearing
cough up mucus
fast, irregular heartbeat
general ill feeling or flu-like symptoms
loss of appetite
pain at site where injected
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
right upper belly pain
sudden weight gain
swelling in feet, ankles, or legs
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
stomach upset or bloating
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for blood pressure like felodipine, nisoldipine
certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin, lomitapide
certain medicines for the heart like disopyramide, dofetilide, dronedarone, eplerenone, quinidine, ranolazine
colchicine (if you have liver or kidney problems)
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
red yeast rice
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain antibiotics like ciprofloxacin, clarithromycin, erythromycin
certain medicines for bladder problems like fesoterodine, solifenacin, tolterodine
certain medicines for cancer like bortezomib, busulfan, dasatanib, docetaxel, erlotinib, ixabepilone, lapatinib, nilotinib, trimetrexate, vinca alkaloids
certain medicines for depression, anxiety, or psychotic disturbances like aripiprazole, buspirone, diazepam, haloperidol, perospirone, quetiapine, risperidone
certain medicines for erectile dysfunction like vardenafil, sildenafil, tadalafil
certain medicines for pain like alfentanil, fentanyl, oxycodone, sufentanil
certain medicines for stomach problems like cimetidine, famotidine, omeprazole, lansoprazole
certain medicines that treat or prevent blood clots like warfarin, dabigatran, rivaroxaban
certain medicines for seizures like carbamazepine, phenytoin
certain medicines for tuberculosis like isoniazid, INH, rifabutin, rifampin, rifapentine
other medicines for fungal infections
steroid medicines like budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
Keep out of the reach of children.
If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease, including angina or heart failure
history of irregular heartbeat
kidney disease or on dialysis
an unusual or allergic reaction to itraconazole, or other antifungal medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. If you are taking this medicine for a long time you may need blood work. Some fungal infections need many weeks or months of treatment to cure.
You may get dizzy or blurred/double vision when taking this medicine. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Do not stand or sit up quickly, especially if you are an older patient.
July 17, 2018