Isoniazid, INH injection
Isoniazid, INH injection
What is this medicine?
ISONIAZID (eye soe NYE a zid) is used to prevent or to treat tuberculosis (TB).
How should I use this medicine?
This medicine is for injection into a muscle. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early. Skipping doses may make the TB resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision or eye pain
dark urine
fever, sore throat
hallucination, loss of contact with reality
loss of appetite
memory problems
nausea, vomiting
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
stomach pain
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
breast enlargement or tenderness
diarrhea
headache
irritation at site where injected
upset stomach
trouble sleeping
What may interact with this medicine?
Do not take this medicine with any of the following medications:
entacapone
green tea
levodopa
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
procarbazine
ranolazine
tolcapone
This medicine may also interact with the following medications:
acetaminophen
alcohol
antacids
medicines for diabetes
medicines for fungal infections like ketoconazole and itraconazole
medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid
theophylline
zalcitabine
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
HIV positive
if you frequently drink alcohol-containing beverages
kidney disease
liver disease
malnutrition
tingling of the fingers or toes, or other nerve disorder
an unusual or allergic reaction to isoniazid, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. You will need blood work done regularly.
You may need to take vitamin supplements while on this medicine. Talk to your doctor about the foods you eat and the vitamins you take.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are diabetic check your blood sugar as directed. Also, you may get a false-positive result for sugar in your urine. Talk with your doctor.
Updated:  
July 17, 2018