Isoniazid, INH
Isoniazid Oral solution
What is this medicine?
ISONIAZID (eye soe NYE a zid) is used to prevent or to treat tuberculosis.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
HIV positive
if you frequently drink alcohol-containing beverages
kidney disease
liver disease
malnutrition
tingling of the fingers or toes, or other nerve disorder
an unusual or allergic reaction to isoniazid, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early. Skipping doses may make the TB resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
entacapone
green tea
levodopa
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
procarbazine
ranolazine
tolcapone
This medicine may also interact with the following medications:
acetaminophen
alcohol
antacids
medicines for diabetes
medicines for fungal infections like ketoconazole and itraconazole
medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid
theophylline
zalcitabine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. You will need blood work done regularly.
You may need to take vitamin supplements while on this medicine. Talk to your doctor about the foods you eat and the vitamins you take. Avoid antacids for 2 hours before and after taking a dose of this medicine.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are diabetic check your blood sugar as directed. Also, you may get a false-positive result for sugar in your urine. Talk with your doctor.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision or eye pain
dark urine
fever, sore throat
hallucination, loss of contact with reality
loss of appetite
memory problems
nausea, vomiting
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
stomach pain
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
breast enlargement or tenderness
diarrhea
headache
upset stomach
trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
Isoniazid Oral tablet
What is this medicine?
ISONIAZID (eye soe NYE a zid) is used to prevent or to treat tuberculosis (TB).
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
HIV positive
if you frequently drink alcohol-containing beverages
kidney disease
liver disease
malnutrition
tingling of the fingers or toes, or other nerve disorder
an unusual or allergic reaction to isoniazid, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the TB resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
entacapone
green tea
levodopa
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
procarbazine
ranolazine
tolcapone
This medicine may also interact with the following medications:
acetaminophen
alcohol
antacids
medicines for diabetes
medicines for fungal infections like ketoconazole and itraconazole
medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid
theophylline
zalcitabine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. You will need blood work done regularly.
You may need to take vitamin supplements while on this medicine. Talk to your doctor about the foods you eat and the vitamins you take. Avoid antacids for 2 hours before and after taking a dose of this medicine.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are diabetic check your blood sugar as directed. Also, you may get a false-positive result for sugar in your urine. Talk with your doctor.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision or eye pain
dark urine
fever, sore throat
hallucination, loss of contact with reality
loss of appetite
memory problems
nausea, vomiting
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
stomach pain
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
breast enlargement or tenderness
diarrhea
headache
upset stomach
trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
Isoniazid Solution for injection
What is this medicine?
ISONIAZID (eye soe NYE a zid) is used to prevent or to treat tuberculosis (TB).
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
HIV positive
if you frequently drink alcohol-containing beverages
kidney disease
liver disease
malnutrition
tingling of the fingers or toes, or other nerve disorder
an unusual or allergic reaction to isoniazid, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for injection into a muscle. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early. Skipping doses may make the TB resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
entacapone
green tea
levodopa
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
procarbazine
ranolazine
tolcapone
This medicine may also interact with the following medications:
acetaminophen
alcohol
antacids
medicines for diabetes
medicines for fungal infections like ketoconazole and itraconazole
medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid
theophylline
zalcitabine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. You will need blood work done regularly.
You may need to take vitamin supplements while on this medicine. Talk to your doctor about the foods you eat and the vitamins you take.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are diabetic check your blood sugar as directed. Also, you may get a false-positive result for sugar in your urine. Talk with your doctor.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision or eye pain
dark urine
fever, sore throat
hallucination, loss of contact with reality
loss of appetite
memory problems
nausea, vomiting
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
stomach pain
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
breast enlargement or tenderness
diarrhea
headache
irritation at site where injected
upset stomach
trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert