DRUGS AND SUPPLEMENTS

Iodixanol

March 21, 2017

Iodixanol injection

What is Iodixanol injection?

IODIXANOL (Visipaque™) is a radiopaque agent used to diagnose certain medical conditions. Iodixanol will be given into your vein or artery by a health care provider. It is usually only given in a hospital or clinic. Iodixanol contains iodine. The iodine in iodixanol will make the blood vessels and surrounding structures in your body opaque or white so they can be photographed by x-rays or CT scans. Usually several pictures are taken as iodixanol moves through your body. Iodixanol can be used to take pictures of the blood vessels around your heart, your brain, your kidney or other structures in your body. It can also be used to help diagnose blood clots. Generic iodixanol injections are not yet available.

What should my health care professional know before I receive Iodixanol?

They need to know if you have any of these conditions:

  • asthma

  • allergic tendencies including eczema, hayfever, or allergies to food or drugs

  • blood clots or strokes

  • dehydration or if you are taking diuretics such as furosemide (Lasix®) or bumetanide (Bumex®)

  • diabetes mellitus

  • heart disease

  • heart failure

  • high blood pressure or pheochromocytoma

  • liver disease

  • lung disease

  • multiple myeloma

  • myasthenia gravis

  • kidney disease or decreased kidney function

  • seizures

  • sickle cell disease

  • thyroid disease

  • an unusual reaction to Iodixanol, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should this medicine be used?

Iodixanol is for injection or infusion into a vein or artery. It is given by a health-care provider in a hospital or clinic setting. Your health care provider may have special instructions for you before you have this procedure. Follow these directions carefully.

What if I miss a dose?

This does not apply.

What drug(s) may interact with Iodixanol?

  • aldesleukin-2 (IL-2)

  • amiodarone

  • antiinflammatory drugs (NSAIDs, such as ibuprofen)

  • amphotericin B

  • certain antibiotics given by injection

  • certain medicines used to control high blood pressure

  • cisplatin

  • cyclosporine

  • entecavir

  • metformin and combination drugs containing metformin

  • water pills

You may or may not be able to take your regular medications during the time of your procedure. Ask your health care provider.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Iodixanol?

Follow all instructions of your health care provider to properly prepare you for your test. Serious side effects are rare. After the test, drink plenty of water to avoid dehydration.

Follow all instructions of your prescriber for care after the test.

What side effects may I notice from receiving Iodixanol?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • an unusual feeling of pain or warmth

  • change in vision

  • chest pain

  • chills or fever

  • decrease or increase in the amount of urine

  • dizziness

  • excessive sweating or intolerance to heat

  • fast or irregular heart beat or pulse

  • hives

  • hot flashes

  • itching

  • nausea or vomiting

  • nervousness

  • pain, swelling, or warmth where ioversol was injected

  • rash

  • seizures

  • swelling of your lips or face

  • tightness in chest or troubled breathing

  • wheezing

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • anxiety

  • bitter or bad taste in your mouth

  • bruising

  • headache

  • nose congestion

  • pain or tingling in your hands or feet

Where can I keep my medicine?

This does not apply. You will only receive iodixanol in a hospital or clinic setting.

Updated:  

March 21, 2017

Sources:  

U.S. FDA-approved Package Insert