IncobotulinumtoxinA injection
IncobotulinumtoxinA injection
What is this medicine?
INCOBOTULINUMTOXINA (IN koh BOT ue LYE num TOX in AY) is a neuro-muscular blocker. This medicine is used to treat eyelid spasms, severe neck muscle spasms, and muscle spasms in the hands and arms. It is also used to treat moderate to severe frown lines on the face.
How should I use this medicine?
This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.
A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
eye irritation
infection
numbness
speech problems
swallowing problems
trouble passing urine or change in the amount of urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
bruising or pain at site where injected
drooping eyelid
dry eyes or mouth
headache
muscle aches, pains
What may interact with this medicine?
aminoglycoside antibiotics like gentamicin, neomycin, tobramycin
antihistamines for allergy, cough and cold
atropine
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
certain medicines for sleep
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
certain medicines that treat or prevent blood clots like warfarin, enoxaparin, and
dalteparin
ipratropium
muscle relaxants
other botulinum toxin injections
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bleeding disorders
cerebral palsy
difficulty swallowing
history of surgery where this medicine is going to be used
infection where this medicine is going to be used
lung or breathing disease, like asthma
myasthenia gravis or other neurologic disease
nerve or muscle disease
surgery plans
an unusual or allergic reaction to botulinum toxin, albumin, sucrose, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor for regular check ups.
This medicine will cause weakness in the muscle where it is injected. Tell your doctor if you feel unusually weak in other muscles. Get medical help right away if you have problems with breathing, swallowing, or talking.
This medicine contains albumin from human blood. It may be possible to pass an infection in this medicine, but no cases have been reported. Talk to your doctor about the risks and benefits of this medicine.
If your activities have been limited by your condition, go back to your regular routine slowly after treatment with this medicine.
You may get muscle weakness, blurred vision, or drooping eyelids. If this happens, do not drive, use machinery, or do other dangerous activities.
Updated:  
July 17, 2018