Sodium Hyaluronate intra-articular injection

July 17, 2018

Sodium Hyaluronate intra-articular injection

What is this medicine?

SODIUM HYALURONATE (SOE dee um hye al yoor ON ate) is used to treat pain in the knee due to osteoarthritis.

How should I use this medicine?

This medicine is for injection into the knee joint. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • dizziness

  • facial flushing

  • pain, tingling, numbness in the hands or feet

  • vision changes if received this medicine during eye surgery

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • bruising at site where injected

  • chills

  • diarrhea

  • fever

  • headache

  • joint pain

  • joint stiffness

  • joint swelling

  • muscle cramps

  • muscle pain

  • nausea, vomiting

  • pain, redness, or irritation at site where injected

  • weak or tired

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders

  • glaucoma

  • infection in the knee joint

  • skin conditions or sensitivity

  • skin infection

  • an unusual allergic reaction to sodium hyaluronate, other medicines, foods, dyes, or preservatives. Different brands of sodium hyaluronate contain different allergens. Some may contain egg. Talk to your doctor about your allergies to make sure that you get the right product.

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

If receiving this medicine for osteoarthritis, limit your activity after you receive your injection. Avoid physical activity for 48 hours following your injection to keep your knee from swelling. Do not stand on your feet for more than 1 hour at a time during the first 48 hours following your injection. Ask your doctor or healthcare professional about when you can begin major physical activity again.


July 17, 2018