Exenatide injection suspension extended-release (autoinjector)
What is this medicine?
EXENATIDE (ex EN a tide) is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
How should I use this medicine?
This medicine is for injection under the skin of your upper leg, stomach area, or upper arm. It is usually given once every week (every 7 days). You will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.
It is important that you put your used autoinjectors in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
diarrhea that continues or is severe
lump or swelling on the neck
signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
unusual stomach upset or pain
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
pain, redness, or irritation at site where injected
What may interact with this medicine?
birth control pills
insulin and other medicines for diabetes
Many medications may cause changes in blood sugar, these include:
alcohol containing beverages
antiviral medicines for HIV or AIDS
aspirin and aspirin-like drugs
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for cholesterol like fenofibrate, gemfibrozil
female hormones, such as estrogens or progestins, birth control pills
male hormones or anabolic steroids
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for allergies, asthma, cold, or cough
medicines for depression, anxiety, or psychotic disturbances
medicines for weight loss
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
quinolone antibiotics such as ciprofloxacin, levofloxacin, ofloxacin
some herbal dietary supplements
steroid medicines such as prednisone or cortisone
Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:
beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
What if I miss a dose?
If you miss a dose, take it as soon as you can, provided your next usual scheduled dose is due at least 3 days later. If you miss a dose and your next usual scheduled dose is due 1 or 2 days later, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses. If you have questions about a missed dose, contact your health care provider for advice.
Where should I keep my medicine?
Keep out of the reach of children.
Store this medicine flat in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Do not use if the medicine has been frozen. Protect from light and excessive heat. Remove from the refrigerator 15 minutes before use. The autoinjector can be kept at room temperature not to exceed 30 degrees C (86 degrees F) for no more than a total of 4 weeks, if needed. Throw away any unused medicine after the expiration date on the label.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
endocrine tumors (MEN 2) or if someone in your family had these tumors
history of pancreatitis
kidney disease or if you are on dialysis
stomach or intestine problems
thyroid cancer or if someone in your family had thyroid cancer
an unusual or allergic reaction to exenatide, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.
Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
Autoinjectors should never be shared. Sharing may result in passing of viruses like hepatitis or HIV.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.
January 10, 2018