Etidronate injection
Etidronate injection
What is this medicine?
ETIDRONATE (e ti DROE nate) reduces calcium loss from bone. This drug helps make healthy bone and slows bone loss in people with Paget's disease. It may also be used in others with heterotropic ossification or high blood calcium.
NOTE: This drug is discontinued in the United States.
How should I use this medicine?
This medicine is given by a healthcare professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions such as skin rash or itching, hives, swelling of the face, lips, throat or tongue
difficulty passing urine
gut or lower back pain
heartburn or stomach pain
increased bone pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste, metallic taste or decreased taste perception
diarrhea or constipation
joint or muscle pain
nausea, vomiting
What may interact with this medicine?
warfarin
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
Keep out of the reach of children.
Once diluted, use injection solution within 48 hours and store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused injection solution.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
asthma
kidney disease
osteomalacia
an unusual or allergic reaction to etidronate, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checkups. It may be some time before you see the benefit from this medicine. Do not stop taking your medicine unless your doctor tells you to. Your doctor may order blood tests or other tests to see how you are doing.
You should make sure you get enough calcium and vitamin D, unless your doctor tells you not to. Discuss the foods you eat and the vitamins you take with your health care professional.
Some people who take this medicine have severe bone, joint, and/or muscle pain. This medicine may also increase your risk for a broken thigh bone. Tell your doctor right away if you have pain in your upper leg or groin. Tell your doctor if you have any pain that does not go away or that gets worse.
Updated:  
July 17, 2018