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Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide oral tablets
What is this medicine?
ELVITEGRAVIR; COBICISTAT; EMTRICITABINE; TENOFOVIR ALAFENAMIDE (el vye TEG ra veer; koe BIS i stat; em tri SIT uh bean; te NOE fo veer) is 3 antiretroviral medicines and a medication booster in 1 tablet. It is used to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heartbeat
muscle pain or weakness
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
medicines for cholesterol like lovastatin, simvastatin
medicines for headaches like dihydroergotamine, ergotamine, methylergonovine
other antiviral medicines for HIV or AIDS
St. John's wort
This medicine may also interact with the following medications:
certain antibiotics like clarithromycin, telithromycin, rifabutin, rifapentine
certain medications for anxiety or sleep like buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem
certain medicines for blood pressure or heart disease like amlodipine, diltiazem, felodipine, metoprolol, nicardipine, nifedipine, timolol, verapamil
certain medicines for depression, anxiety, or psychiatric disturbances
certain medicines for erectile dysfunction like avanafil, sildenafil, tadalafil, vardenafil
certain medicines for fungal infection like itraconazole, ketoconazole, voriconazole
certain medicines that treat or prevent blood clots like warfarin, apixaban, betrixaban, dabigatran, edoxaban, and rivaroxaban
female hormones, like estrogens and progestins and birth control pills
medicines for infection like acyclovir, cidofovir, valacyclovir, ganciclovir, valganciclovir
medicines for irregular heart beat like amiodarone, bepridil, digoxin, disopyramide, dofetilide, flecainide, lidocaine, mexiletine, propafenone, quinidine
phenothiazines like perphenazine, risperidone, thioridazine
steroid medicines like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, triamcinolone
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature below 30 degrees C (86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an unusual or allergic reaction to elvitegravir, cobicistat, emtricitabine, tenofovir, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
If you have hepatitis B, talk to your doctor if you plan to stop this medicine. The symptoms of hepatitis B may get worse if you stop this medicine.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom.
November 22, 2020