What is doxacurium injection?
DOXACURIUM (Nuromax®) is a muscle relaxant. It relaxes muscles in patients who are having surgery or in patients who are on breathing machines (ventilators). Generic doxacurium injection is not available.
What should my health care professional know before I receive doxacurium?
They need to know if you have any of these conditions:
lung disease or breathing difficulties
history of malignant hyperthermia during prior surgery
neuromuscular disorder such as myasthenia gravis
other chronic illness
an unusual or allergic reaction to doxacurium, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
Doxacurium is for injection or infusion into a vein. It is given only by a health-care professional in a hospital or clinic setting.
Contact your health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
Doxacurium is given only by a health-care professional in a hospital or clinic setting.
What drug(s) may interact with doxacurium?
tetracyclines or clindamycin
magnesium or calcium salts
medicines for angina or high blood pressure
medicines for pain
medicines to control heart rhythm
medicines to control seizures such as phenytoin or carbamazepine
certain antibiotics given by injection
edrophonium or neostigmine
polymyxin B or bacitracin
local anesthetics such as procaine
succinylcholine or other muscle relaxants
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking doxacurium?
You will be carefully monitored for side effects while you receive doxacurium, and for some time afterwards.
What side effects may I notice from receiving doxacurium?
Side effects that you should report to your prescriber or health care professional as soon as possible:
fainting, dizziness or lightheadedness
pain, redness, swelling or irritation at the injection site
pounding heartbeat or slow heartbeat
difficulty breathing or wheezing
unusual muscle weakness or tiredness
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
flushing (reddening of the skin)
Where can I keep my medicine?
Doxacurium is given only by a health-care professional in a hospital or clinic setting. Doxacurium is stored at room temperature at 15 to 25 degrees C (59—77 degrees F).
March 21, 2017
U.S. FDA-approved Package Insert