Dolasetron
Dolasetron Mesylate Monohydrate Oral tablet
What is this medicine?
DOLASETRON (dol A se tron) is used to prevent nausea and vomiting caused by chemotherapy.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
history of irregular heartbeat
kidney disease
low levels of magnesium or potassium in the blood
an unusual or allergic reaction to dolasetron, granisetron, ondansetron, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not take this medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
pimozide
thioridazine
ziprasidone
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
beta-blockers like atenolol, metoprolol, propranolol
calcium channel blockers like diltiazem, verapamil
certain medicines for depression, anxiety, or psychotic disturbances
cimetidine
daunorubicin
digoxin
diuretics
doxorubicin
epirubicin
fentanyl
flecainide
linezolid
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
methylene blue (injected into a vein)
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
quinidine
rifampin
tramadol
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Check with your doctor or health care professional right away if you have any sign of an allergic reaction.
Do not drink alcohol while taking this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
chest tightness
confusion
dizziness
fast or irregular heartbeat
feeling faint or lightheaded, falls
fever and chills
loss of balance or coordination
seizures
sweating
swelling of the feet or hands
tremors
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation or diarrhea
headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
Dolasetron Mesylate Monohydrate Solution for injection
What is this medicine?
DOLASETRON (dol A se tron) is used to treat and prevent nausea and vomiting after surgery.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
history of irregular heartbeat
kidney disease
low levels of magnesium or potassium in the blood
an unusual or allergic reaction to dolasetron, granisetron, ondansetron, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for infusion into a vein. It is given by a health-care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this medicine may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
pimozide
thioridazine
ziprasidone
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
beta-blockers like atenolol, metoprolol, propranolol
calcium channel blockers like diltiazem, verapamil
certain medicines for depression, anxiety, or psychotic disturbances
cimetidine
daunorubicin
digoxin
diuretics
doxorubicin
epirubicin
fentanyl
flecainide
linezolid
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
methylene blue (injected into a vein)
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
quinidine
rifampin
tramadol
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
chest tightness
confusion
dizziness
fast or irregular heartbeat
feeling faint or lightheaded, falls
fever and chills
loss of balance or coordination
seizures
sweating
swelling of the feet or hands
tremors
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation or diarrhea
headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert