Diazepam rectal gel
What is this medicine?
DIAZEPAM (dye AZ e pam) is a benzodiazepine. It is used to treat certain types of seizures.
How should I use this medicine?
Patients and caregivers should thoroughly read and understand how to use medicine. Follow the directions given to you by your doctor or health care professional. You may be prescribed a second dose. If a second dose is needed, give it 4 to 12 hours after the first dose. If you have any questions about the medicine, you may call 1-877-361-2719 or visit www.diastat.com. This medicine should be used to treat no more than five episodes per month and no more than one episode every five days.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
loss of balance or coordination
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
suicidal thoughts or other mood changes
trouble passing urine or change in the amount of urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Do not take this medicine with any of the following medications:
narcotic medicines for cough
This medicine may also interact with the following medications:
antihistamines for allergy, cough and cold
certain antibiotics like clarithromycin, erythromycin, rifampin
certain medicines for anxiety or sleep
certain medicines for blood pressure, heart disease, irregular heartbeat
certain medicines for depression, like amitriptyline, fluoxetine, sertraline
certain medicines for fungal infections like ketoconazole, itraconazole, clotrimazole
certain medicines for psychotic disturbances
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, primidone, valproate
general anesthetics like lidocaine, pramoxine, tetracaine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines that relax muscles for surgery
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
What if I miss a dose?
This does not apply; this medicine is not for regular use.
Where should I keep my medicine?
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Protect from light.
This medicine may cause harm and death if it is taken by other adults, children, or pets. Return medicine that has not been used to an official disposal site. Contact the DEA at 1-800-882-9539 or your city/county government to find a site. If you cannot return the medicine, flush it down the toilet. Do not use the medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions
an alcohol or drug abuse problem
bipolar disorder, depression, psychosis or other mental health condition
lung or breathing disease
seizures or a history of seizures
an unusual or allergic reaction to diazepam, other benzodiazepines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
July 17, 2018