Dextromethorphan; Quinidine oral capsules

March 03, 2019

Dextromethorphan; Quinidine oral capsules

What is this medicine?

DEXTROMETHORPHAN; QUINIDINE (dex troe meth OR fan; KWIN i deen) is a combination of two medicines used to treat pseudobulbar affect (PBA), a condition that causes uncontrollable, sudden, and frequent episodes of laughing and/or crying.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • changes in vision

  • chills

  • confusion

  • decreased hearing

  • fast or irregular heartbeat

  • feeling faint or lightheaded, falls

  • fever

  • muscle pain

  • ringing of the ears

  • sensitivity to light

  • unusual bleeding or bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough

  • diarrhea

  • dizziness

  • drowsiness

  • headache

  • nausea, vomiting

  • stomach pain

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • arsenic trioxide

  • certain antipsychotics like chlorpromazine, clozapine, haloperidol, mesoridazine, olanzapine, perphenazine, pimozide, risperidone, sertindole, thioridazine, ziprasidone

  • certain medicines for irregular heart beat like amiodarone, bepridil, dofetilide, encainide, flecainide, propafenone, quinidine

  • certain medicines used to treat infections like chloroquine, clarithromycin, erythromycin, pentamidine, posaconazole

  • certain medicines used for nausea like dolasetron, droperidol, ondansetron, palonosetron

  • cisapride

  • cyclobenzaprine

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • mefloquine

  • methadone

  • quinine

  • ranolazine

This medicine may also interact with the following medications:

  • alcohol

  • aprepitant

  • certain antiviral medicines for HIV or AIDS

  • certain medicines for depression or anxiety

  • certain medicines for fungal infections like fluconazole, ketoconazole, and itraconazole

  • codeine

  • digoxin

  • diltiazem

  • grapefruit juice

  • hydrocodone

  • memantine

  • tacrolimus

  • telavancin

  • telithromycin

  • tetrabenazine

  • vardenafil

  • verapamil

  • vorinostat

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

This medicine may cause accidental overdose and death if it taken by other adults, children, or pets. Mix any unused medicine with a substance like cat litter or coffee grounds. Then throw the medicine away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medicine after the expiration date.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • dementia

  • heart disease

  • history of drug abuse or alcohol abuse problem

  • history of low blood counts caused by a medicine

  • history of irregular heartbeat

  • kidney disease

  • liver disease

  • low levels of magnesium or potassium in the blood

  • myasthenia gravis

  • an unusual or allergic reaction to dextromethorphan, quinidine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.

You may get dizzy. Contact your doctor right away if you feel faint or have fainting spells while taking this medicine. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks; they can make you more dizzy.


March 03, 2019