Desloratadine; Pseudoephedrine
Desloratadine, Pseudoephedrine Sulfate Oral tablet, extended release 12 hour
What is this medicine?
DESLORATADINE; PSEUDOEPHEDRINE (des lor AT a deen; soo doe e FED rin) is a combination of an antihistamine and a decongestant. This medicine is used to treat the symptoms of allergies. It reduces congestion, sneezing, runny nose, and itching.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
difficulty urinating
disease of the blood vessels or heart
glaucoma
high blood pressure
kidney disease
liver disease
thyroid disease
an unusual or allergic reaction to desloratadine, loratadine, pseudoephedrine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take with or without food. Do not break, chew, or crush. Take your doses at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Patients over 60 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
digoxin
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for allergies, colds, breathing difficulties
medicines for headaches like dihydroergotamine, ergotamine
procarbazine
stimulants
This medicine may also interact with the following medications:
linezolid
medicines for depression like amitriptyline, nortriptyline
medicines for heart disease or blood pressure like atenolol, clonidine, doxazosin, mecamylamine, or reserpine
methyldopa
nitroglycerin
sodium lactate
some medicines for sleep during surgery
St. John's wort
theophylline
tizanidine
yohimbine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for checks on your progress. Tell your doctor if your symptoms do not improve.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
breathing problems
difficulty urinating
fast, irregular heartbeat
feeling faint, dizzy
high blood pressure
infection
nervousness, agitation
tremor, muscle contractions
unusually weak
yellowing of eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry mouth
feeling tired
headache
loss of appetite
nausea
trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
Desloratadine, Pseudoephedrine Sulfate Oral tablet, extended release 24 hour
What is this medicine?
DESLORATADINE; PSEUDOEPHEDRINE (des lor AT a deen; soo doe e FED rin) is a combination of an antihistamine and a decongestant. This medicine is used to treat the symptoms of allergies. It reduces congestion, sneezing, runny nose, and itching.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
difficulty urinating
disease of the blood vessels or heart
glaucoma
high blood pressure
kidney disease
liver disease
thyroid disease
an unusual or allergic reaction to desloratadine, loratadine, pseudoephedrine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take with or without food. Do not break, chew, or crush. Take your doses at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Patients over 60 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
digoxin
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for allergies, colds, breathing difficulties
medicines for headaches like dihydroergotamine, ergotamine
procarbazine
stimulants
This medicine may also interact with the following medications:
linezolid
medicines for depression like amitriptyline, nortriptyline
medicines for heart disease or blood pressure like atenolol, clonidine, doxazosin, mecamylamine, or reserpine
methyldopa
nitroglycerin
sodium lactate
some medicines for sleep during surgery
St. John's wort
theophylline
tizanidine
yohimbine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for checks on your progress. Tell your doctor if your symptoms do not improve.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
breathing problems
difficulty urinating
fast, irregular heartbeat
feeling faint, dizzy
high blood pressure
infection
nervousness, agitation
tremor, muscle contractions
unusually weak
yellowing of eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry mouth
feeling tired
headache
loss of appetite
nausea
trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert