Denileukin Diftitox injection
Denileukin Diftitox injection
What is this medicine?
DENILEUKIN DIFTITOX (DEN i loo kin DIF ti toks) is a fusion protein and a chemotherapy drug. It is used to treat cutaneous T-cell lymphoma.
How should I use this medicine?
This drug is given as an infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain
fast heartbeat
fast weight gain
fever or chills
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
swelling of the ankles, feet, hands
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
cough
diarrhea
headache
joint pain
vomiting
What may interact with this medicine?
Interaction studies have not been performed.
What if I miss a dose?
Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
low level of albumin in the blood
an unusual or allergic reaction to denileukin deftitox, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine. You may need blood work done while you are taking this medicine.
This medicine can cause serious allergic reactions. To reduce your risk you may need to take medicine before treatment with this medicine. Take your medicine as directed.
Do not become pregnant while taking this medicine or for 7 days after the last dose. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 7 days after the last dose.
Updated:  
February 28, 2020