Cyclobenzaprine
Cyclobenzaprine Hydrochloride Oral capsule, extended-release
What is this medicine?
CYCLOBENZAPRINE (sye kloe BEN za preen) is a muscle relaxer. It is used to treat muscle pain, spasms, and stiffness.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
irregular heartbeat
liver disease
past heart attack
thyroid problem
an unusual or allergic reaction to cyclobenzaprine, tricyclic antidepressants, lactose, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. If this medicine upsets your stomach, take it with food or milk. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
droperidol
flecainide
grepafloxacin
halofantrine
levomethadyl
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
nilotinib
pimozide
probucol
sertindole
thioridazine
ziprasidone
This medicine may also interact with the following medications:
abarelix
alcohol
certain medicines for cancer
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for infection like alfuzosin, chloroquine, clarithromycin, levofloxacin, mefloquine, pentamidine, troleandomycin
certain medicines for irregular heart beat
certain medicines used for sleep or numbness during surgery or procedure
contrast dyes
dolasetron
guanethidine
methadone
octreotide
ondansetron
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
palonosetron
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
tramadol
vardenafil
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Drinking water, chewing sugarless gum, or sucking on hard candy may help.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain
fast heartbeat
hallucinations
seizures
vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Cyclobenzaprine Hydrochloride Oral tablet
What is this medicine?
CYCLOBENZAPRINE (sye kloe BEN za preen) is a muscle relaxer. It is used to treat muscle pain, spasms, and stiffness.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease, irregular heartbeat, or previous heart attack
liver disease
thyroid problem
an unusual or allergic reaction to cyclobenzaprine, tricyclic antidepressants, lactose, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. If this medicine upsets your stomach, take it with food or milk. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cisapride
dofetilide
dronedarone
droperidol
flecainide
grepafloxacin
halofantrine
levomethadyl
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
nilotinib
pimozide
probucol
sertindole
thioridazine
ziprasidone
This medicine may also interact with the following medications:
abarelix
alcohol
certain medicines for cancer
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for infection like alfuzosin, chloroquine, clarithromycin, levofloxacin, mefloquine, pentamidine, troleandomycin
certain medicines for an irregular heart beat
certain medicines used for sleep or numbness during surgery or procedure
contrast dyes
dolasetron
guanethidine
methadone
octreotide
ondansetron
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
palonosetron
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
tramadol
vardenafil
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Check with your doctor or health care professional if your condition does not improve within 1 to 3 weeks.
You may get drowsy or dizzy when you first start taking the medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly.
Your mouth may get dry. Drinking water, chewing sugarless gum, or sucking on hard candy may help.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain
fast heartbeat
hallucinations
seizures
vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert