Codeine Phosphate, Chlorpheniramine Maleate Oral tablet, extended-release
What is this medicine?
CHLORPHENIRAMINE; CODEINE (klor fen IR a meen; KOE deen) is a combination of an antihistamine and cough suppressant. It is used to treat the symptoms of cough, allergies, and colds.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Do not crush, cut or chew this medicine. You can take it with or without food. If it upsets your stomach, take it with food. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
trouble passing urine or change in the amount of urine
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Do not take this medication with any of the following medicines:
certain medicines for anxiety or sleep
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, primidone
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
local anesthetics like lidocaine, pramoxine, tetracaine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines that relax muscles for surgery
other antihistamines for allergy, cough and cold
other narcotic medicines for pain or cough
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain antibiotics like erythromycin and clarithromycin
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for fungal infections like ketoconazole and itraconazole
certain medicines for irregular heart beat like amiodarone, propafenone, quinidine
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Keep container tightly closed. Throw away any unused medicine after the expiration date. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
history of a drug or alcohol abuse problem
lung or breathing disease, like asthma
other chronic illness
stomach or intestine problems
an unusual or allergic reaction to chlorpheniramine, codeine, other pain medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not improve or if they get worse.
If you have been taking this medicine for a long time, do not suddenly stop taking it because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a nonmedical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
There are different types of narcotic medicines (opiates). If you take more than one type at the same time or if you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Children may be at higher risk for side effects. If your child has slow breathing, noisy breathing, confusion, or unusual sleepiness, stop giving this medicine and get medical help right away.
Immediately call your physician or get emergency help if you are breast-feeding and your baby is sleepier than usual, is limp, or has difficulty breast-feeding or breathing.
The medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
March 22, 2017