Cisapride
Cisapride Oral suspension
What is this medicine?
CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked. This medicine in only available from your doctor, who must register with the drug company and meet certain criteria for the use of this drug. This medicine has not been available in pharmacies since August 2000. For information, the manufacturer has provided the following toll-free number (877) 795-4247.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
eating disorder, like anorexia or bulimia
heart disease or heart failure
heart rhythm problems
heart valve problems
history of low levels of calcium, potassium, or magnesium
kidney disease
liver disease
lung disease
stomach bleeding, blockage, or ulceration
an unusual or allergic reaction to cisapride, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take this medicine on an empty stomach, at least 15 minutes before eating and at bedtime. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alfuzosin
antiviral medicines for HIV or AIDS
apomorphine
aprepitant
arsenic trioxide
certain antibiotics like ciprofloxacin, clarithromycin, dalfopristin;quinupristin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
certain medicines for cancer like daunorubicin, doxorubixin
certain medicines for depression, anxiety, or other psychotic disturbances like clozapine, haloperidol, isoniazid, pimozide, risperidone, ziprasidone
certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like amiodarone, bretylium, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol
chloroquine
cimetidine
conivaptan
cyclobenzaprine
cyclosporine
danazol
diltiazem
dolasetron
droperidol
ethinyl estradiol
general and local anesthetics
grapefruit juice
halofantrine
hawthorn
imatinib
isoniazid
methadone
mifepristone
nicardipine
octreotide
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
palonosetron
phenothiazines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine
quinine
ranolazine
sodium phosphates
tacrolimus
verapamil
zafirlukast
zileuton
This medicine may also interact with the following medications:
diuretics
insulin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. For this medicine to work properly it is important to make lifestyle changes. Eat smaller meals, elevate the head of your bed 6 to 8 inches, avoid high-fat foods, chocolate, alcohol, smoking, caffeine and carbonated drinks.
If you have any fainting spells or rapid or irregular heartbeat, stop taking this drug immediately. Contact your health care professional right away for evaluation.
Do not drink grapefruit juice while you are taking this medicine. Grapefruit juice could increase your risk of having serious side effects from this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
feeling faint or lightheaded, falls
rapid or irregular heartbeat
unusually weak or tired
vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea or constipation
headache
nausea
stomach pain
stuffy nose
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
Cisapride Oral tablet
What is this medicine?
CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked. This medicine in only available from your doctor, who must register with the drug company and meet certain criteria for the use of this drug. Cisapride has not been available in pharmacies since August 2000. For information, the manufacturer has provided the following toll-free number (877) 795-4247.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
eating disorder, like anorexia or bulimia
heart disease or heart failure
heart rhythm problems
heart valve problems
history of low levels of calcium, potassium, or magnesium
kidney disease
liver disease
lung disease
stomach bleeding, blockage, or ulceration
an unusual or allergic reaction to cisapride, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the label. Take this medicine on an empty stomach, at least 15 minutes before eating and at bedtime. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alfuzosin
antiviral medicines for HIV or AIDS
apomorphine
aprepitant
arsenic trioxide
certain antibiotics like ciprofloxacin, clarithromycin, dalfopristin;quinupristin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
certain medicines for cancer like daunorubicin, doxorubicin, imatinib
certain medicines for depression, anxiety, or other psychotic disturbances like clozapine, haloperidol, pimozide, risperidone, ziprasidone
certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like amiodarone, disopyramide, bretylium, dofetilide, dronedarone, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol
chloroquine
cimetidine
conivaptan
cyclobenzaprine
cyclosporine
danazol
diltiazem
dolasetron
droperidol
ethinyl estradiol
general and local anesthetics
grapefruit juice
halofantrine
hawthorn
imatinib
isoniazid
methadone
mifepristone
nicardipine
octreotide
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
palonosetron
phenothiazines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine
quinine
ranolazine
sodium phosphates
tacrolimus
verapamil
zafirlukast
zileuton
This medicine may also interact with the following medications:
diuretics
insulin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. For this medicine to work properly it is important to make lifestyle changes. Eat smaller meals, elevate the head of your bed 6 to 8 inches, avoid high-fat foods, chocolate, alcohol, smoking, caffeine and carbonated drinks.
If you have any fainting spells or rapid or irregular heartbeat, stop taking this drug immediately. Contact your health care professional right away for evaluation.
Do not drink grapefruit juice while you are taking this medicine. Grapefruit juice could increase your risk of having serious side effects from this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
breathing problems
fainting or falling spells
rapid or irregular heartbeat
unusually weak or tired
vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea or constipation
headache
nausea
stomach pain
stuffy nose
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
Updated:
March 21, 2017
Sources:
U.S. FDA-approved Package Insert