Captopril, Hydrochlorothiazide Oral tablet
What is this medicine?
CAPTOPRIL; HYDROCHLOROTHIAZIDE (KAP toe pril; hye droe klor oh THYE a zide) is a combination of a diuretic and an ACE inhibitor. It is used to treat high blood pressure.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bone marrow disease
heart or blood vessel disease
if you are on a special diet like a low salt diet
immune system problems, like lupus
previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
recent heart attack or stroke
an unusual or allergic reaction to captopril, hydrochlorothiazide, sulfa drugs, other medicines, insect venom, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before meals. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
barbiturates like phenobarbital
blood pressure medicines
corticosteroids like prednisone
diuretics, especially potassium-sparing diuretics like triamterene, spironolactone or amiloride
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for angina like nitroglycerin
medicines that treat or prevent blood clots like warfarin
medicines used to treat gout
NSAIDs like ibuprofen
potassium salts or potassium supplements
prescription pain medicines
skeletal muscle relaxants like tubocurarine
some cholesterol-lowering medications like cholestyramine or colestipol
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. Call your doctor or health care professional if you notice an irregular or fast heart beat.
You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.
Avoid salt substitutes unless you are told otherwise by your doctor or health care professional.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
decreased amount of urine passed
fast or irregular heart beat
feeling faint or lightheaded, falls
nausea and vomiting
persistent dry cough
redness, blistering, peeling or loosening of the skin, including inside the mouth
swelling of your hands or feet
unusual bleeding or bruising
worsened gout pain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature below 30 degrees C (86 degrees F). Protect from moisture and light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
March 21, 2017
U.S. FDA-approved Package Insert